Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/SOD1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "173", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Peroxisome" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:53.872332" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI269" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/173/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/173/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DAO" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/173/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/173/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/173/?format=api" } }, { "type": "GeneCombination", "id": "174", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:53.906411" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI270" }, { "type": "Combination", "id": "OLI635" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/174/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/174/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SETX" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/174/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/174/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/174/?format=api" } }, { "type": "GeneCombination", "id": "184", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases", "Cellular responses to external stimuli", "Huntington disease" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:54.197524" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI280" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/184/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/184/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ANG" }, { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/184/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/184/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/184/?format=api" } }, { "type": "GeneCombination", "id": "216", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:55.753871" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI328" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/216/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/216/combinations/?format=api" } }, "genes": { "meta": { "count": 7 }, "data": [ { "type": "Gene", "id": "ARHGEF28" }, { "type": "Gene", "id": "AVPR2" }, { "type": "Gene", "id": "EPHB3" }, { "type": "Gene", "id": "FAM170A" }, { "type": "Gene", "id": "POU2F1" }, { "type": "Gene", "id": "RDX" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/216/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/216/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/216/?format=api" } }, { "type": "GeneCombination", "id": "217", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Metabolic pathways", "Signaling by Interleukins", "Immune System", "Pathways in cancer", "Metabolism of proteins", "Post-translational protein modification", "Cytokine Signaling in Immune system", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:55.857615" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI329" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/217/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "ALOX15" }, { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "COL4A1" }, { "type": "Gene", "id": "FBXW8" }, { "type": "Gene", "id": "NOB1" }, { "type": "Gene", "id": "PMM2" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "TPP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/217/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/?format=api" } }, { "type": "GeneCombination", "id": "218", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MYH11, SOD1)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.060472" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI330" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/218/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/218/combinations/?format=api" } }, "genes": { "meta": { "count": 14 }, "data": [ { "type": "Gene", "id": "ADA2" }, { "type": "Gene", "id": "APTX" }, { "type": "Gene", "id": "BICD2" }, { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "CHRNE" }, { "type": "Gene", "id": "LAMB2" }, { "type": "Gene", "id": "MYH11" }, { "type": "Gene", "id": "NME8" }, { "type": "Gene", "id": "PRRT2" }, { "type": "Gene", "id": "QARS1" }, { "type": "Gene", "id": "SLC26A10" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "UNC13A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/218/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/218/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/218/?format=api" } }, { "type": "GeneCombination", "id": "219", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(HEXB, SOD1)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.184376" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI331" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/219/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/219/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "ARHGEF10" }, { "type": "Gene", "id": "FAM126A" }, { "type": "Gene", "id": "GRWD1" }, { "type": "Gene", "id": "HEXB" }, { "type": "Gene", "id": "ITPR1" }, { "type": "Gene", "id": "MARS1" }, { "type": "Gene", "id": "POLG2" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/219/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/219/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/219/?format=api" } }, { "type": "GeneCombination", "id": "220", "attributes": { "gene_relationship": [ "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.327376" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI332" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/220/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/220/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "ADGRB2" }, { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "CHRNB1" }, { "type": "Gene", "id": "GALC" }, { "type": "Gene", "id": "HTT" }, { "type": "Gene", "id": "ITPR1" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "XK" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/220/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/220/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/220/?format=api" } }, { "type": "GeneCombination", "id": "221", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.474206" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI333" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/221/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/221/combinations/?format=api" } }, "genes": { "meta": { "count": 9 }, "data": [ { "type": "Gene", "id": "ADCY5" }, { "type": "Gene", "id": "AHNAK" }, { "type": "Gene", "id": "ANG" }, { "type": "Gene", "id": "ATP7A" }, { "type": "Gene", "id": "KIAA1755" }, { "type": "Gene", "id": "KMT2C" }, { "type": "Gene", "id": "MYOM1" }, { "type": "Gene", "id": "POU2F1" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/221/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/221/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/221/?format=api" } }, { "type": "GeneCombination", "id": "222", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:56.554381" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI334" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/222/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "PGAM4" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/222/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/?format=api" } }, { "type": "GeneCombination", "id": "223", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Immune System", "Metabolism of lipids", "Metabolism" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.642986" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI335" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/223/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/223/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CAPN1" }, { "type": "Gene", "id": "CHAT" }, { "type": "Gene", "id": "GALC" }, { "type": "Gene", "id": "KIF1B" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/223/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/223/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/223/?format=api" } }, { "type": "GeneCombination", "id": "297", "attributes": { "gene_relationship": [ "Directly interacting", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Monogenic experiments only" ], "protein_interactions": [ "(OPTN, SOD1)" ], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:01.068096" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI439" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/297/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/297/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "OPTN" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/297/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/297/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/297/?format=api" } }, { "type": "GeneCombination", "id": "298", "attributes": { "gene_relationship": [ "Involved in the same disease", "Directly interacting", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [ "(SOD1, SQSTM1)" ], "common_pathways": [ "Signaling by Interleukins", "Immune System", "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis", "Cytokine Signaling in Immune system" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:01.098760" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI440" }, { "type": "Combination", "id": "OLI636" }, { "type": "Combination", "id": "OLI1700" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/298/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/298/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/298/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/298/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/298/?format=api" } }, { "type": "GeneCombination", "id": "434", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:08.691350" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI634" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/434/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/434/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CCNF" }, { "type": "Gene", "id": "CFAP410" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/434/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/434/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/434/?format=api" } }, { "type": "GeneCombination", "id": "451", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:09.555886" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI658" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/451/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/451/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MATR3" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/451/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/451/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/451/?format=api" } }, { "type": "GeneCombination", "id": "552", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:15.965955" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI764" }, { "type": "Combination", "id": "OLI1621" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/552/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/552/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "C9orf72" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/552/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/552/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/552/?format=api" } }, { "type": "GeneCombination", "id": "559", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:16.353313" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI775" }, { "type": "Combination", "id": "OLI1701" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/559/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/559/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FUS" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/559/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/559/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/559/?format=api" } }, { "type": "GeneCombination", "id": "561", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:16.402216" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI777" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/561/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/561/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "UBQLN2" } ], 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