Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/727/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "727",
        "attributes": {
            "gene_relationship": [
                "Monogenic experiments only",
                "Relevant pathways for phenotype"
            ],
            "protein_interactions": [],
            "common_pathways": [],
            "genecomb_metascore": 0,
            "lastmodified": "2024-03-01T14:56:56.455724"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI970"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/727/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/727/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 6
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "FUS"
                    },
                    {
                        "type": "Gene",
                        "id": "NEK1"
                    },
                    {
                        "type": "Gene",
                        "id": "PON1"
                    },
                    {
                        "type": "Gene",
                        "id": "SETX"
                    },
                    {
                        "type": "Gene",
                        "id": "SOD1"
                    },
                    {
                        "type": "Gene",
                        "id": "VAPB"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/727/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/727/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/727/?format=api"
        }
    }
}