Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/PROKR2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "10", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:45.660586" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI014" }, { "type": "Combination", "id": "OLI1164" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/10/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/10/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/10/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/10/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/10/?format=api" } }, { "type": "GeneCombination", "id": "31", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.719544" }, "relationships": { "combination_set": { "meta": { "count": 8 }, "data": [ { "type": "Combination", "id": "OLI036" }, { "type": "Combination", "id": "OLI196" }, { "type": "Combination", "id": "OLI204" }, { "type": "Combination", "id": "OLI833" }, { "type": "Combination", "id": "OLI1269" }, { "type": "Combination", "id": "OLI1272" }, { "type": "Combination", "id": "OLI1338" }, { "type": "Combination", "id": "OLI1356" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/31/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/31/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/31/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/31/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/31/?format=api" } }, { "type": "GeneCombination", "id": "116", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "GPCR downstream signalling", "Signal Transduction", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.789137" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI165" }, { "type": "Combination", "id": "OLI207" }, { "type": "Combination", "id": "OLI1288" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/116/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/116/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/116/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/116/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/116/?format=api" } }, { "type": "GeneCombination", "id": "265", "attributes": { "gene_relationship": [ "Directly interacting", "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "GPCR downstream signalling", "Signal Transduction", "Peptide ligand-binding receptors", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.074784" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI396" }, { "type": "Combination", "id": "OLI834" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/265/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/265/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROK2" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/265/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/265/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/265/?format=api" } }, { "type": "GeneCombination", "id": "257", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.665277" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI373" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/257/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/257/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "GNRH1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/257/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/257/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/257/?format=api" } }, { "type": "GeneCombination", "id": "442", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:09.219553" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI648" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/442/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/442/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PLXNA1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/442/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/442/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/442/?format=api" } }, { "type": "GeneCombination", "id": "478", "attributes": { "gene_relationship": [ "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:10.630832" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI689" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/478/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/478/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/478/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/478/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/478/?format=api" } }, { "type": "GeneCombination", "id": "596", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:17.912074" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI816" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/596/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/596/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "RNF216" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/596/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/596/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/596/?format=api" } }, { "type": "GeneCombination", "id": "616", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:18.953084" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI848" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/616/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/616/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "PNPLA6" }, { "type": "Gene", "id": "POLR3A" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "TRAPPC9" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/616/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/616/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/616/?format=api" } }, { "type": "GeneCombination", "id": "617", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.002285" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI849" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/617/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/617/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DCAF17" }, { "type": "Gene", "id": "DMXL2" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/617/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/617/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/617/?format=api" } }, { "type": "GeneCombination", "id": "619", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.070279" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI851" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/619/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/619/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CNTN2" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/619/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/619/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/619/?format=api" } }, { "type": "GeneCombination", "id": "622", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Nervous system development", "Axon guidance", "Pathways in cancer", "Developmental Biology", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.234972" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI855" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/622/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/622/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DCC" }, { "type": "Gene", "id": "MET" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/622/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/622/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/622/?format=api" } }, { "type": "GeneCombination", "id": "626", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.391627" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI859" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/626/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/626/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MTOR" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/626/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/626/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/626/?format=api" } }, { "type": "GeneCombination", "id": "629", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.714371" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI862" }, { "type": "Combination", "id": "OLI892" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/629/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/629/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "ROBO3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/629/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/629/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/629/?format=api" } }, { "type": "GeneCombination", "id": "630", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.777894" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI863" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/630/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/630/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "EBF2" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "RELN" }, { "type": "Gene", "id": "SEMA3A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/630/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/630/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/630/?format=api" } }, { "type": "GeneCombination", "id": "631", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.843239" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI864" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/631/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/631/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DLX5" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/631/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/631/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/631/?format=api" } }, { "type": "GeneCombination", "id": "632", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.939861" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI865" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/632/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/632/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "HGF" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/632/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/632/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/632/?format=api" } }, { "type": "GeneCombination", "id": "637", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:20.219114" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI870" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/637/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/637/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "EFNA5" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/637/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/637/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/637/?format=api" } }, { "type": "GeneCombination", "id": "653", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Developmental Biology", "Peptide ligand-binding receptors", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:21.247449" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI887" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/653/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/653/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "EDNRB" }, { "type": "Gene", "id": "PAX6" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "RELN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/653/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/653/genes/?format=api" } } }, 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