Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1080/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CHD7", "attributes": { "go_molecular_function": [ "['chromatin binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'protein binding', 'ATP hydrolysis activity', 'DNA helicase activity', 'promoter-specific chromatin binding', 'ATP binding']" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9P2D1", "ensembl_id": "None", "entrez_id": "ENSG00000171316", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.704701" }, "relationships": { "variant_set": { "meta": { "count": 70 }, "data": [ { "type": "SmallVariant", "id": "39" }, { "type": "SmallVariant", "id": "275" }, { "type": "SmallVariant", "id": "708" }, { "type": "SmallVariant", "id": "771" }, { "type": "SmallVariant", "id": "772" }, { "type": "SmallVariant", "id": "974" }, { "type": "SmallVariant", "id": "1158" }, { "type": "SmallVariant", "id": "1215" }, { "type": "SmallVariant", "id": "1495" }, { "type": "SmallVariant", "id": "1830" }, { "type": "SmallVariant", "id": "1853" }, { "type": "SmallVariant", "id": "1860" }, { "type": "SmallVariant", "id": "1882" }, { "type": "SmallVariant", "id": "1899" }, { "type": "SmallVariant", "id": "1905" }, { "type": "SmallVariant", "id": "1911" }, { "type": "SmallVariant", "id": "1912" }, { "type": "SmallVariant", "id": "1954" }, { "type": "SmallVariant", "id": "1968" }, { "type": "SmallVariant", "id": "2078" }, { "type": "SmallVariant", "id": "2401" }, { "type": "SmallVariant", "id": "2403" }, { "type": "SmallVariant", "id": "2494" }, { "type": "SmallVariant", "id": "2496" }, { "type": "SmallVariant", "id": "2500" }, { "type": "SmallVariant", "id": "2509" }, { "type": "SmallVariant", "id": "2518" }, { "type": "SmallVariant", "id": "2659" }, { "type": "SmallVariant", "id": "2661" }, { "type": "SmallVariant", "id": "2668" }, { "type": "SmallVariant", "id": "2674" }, { "type": "SmallVariant", "id": "2679" }, { "type": "SmallVariant", "id": "2702" }, { "type": "SmallVariant", "id": "2704" }, { "type": "SmallVariant", "id": "2706" }, { "type": "SmallVariant", "id": "2716" }, { "type": "SmallVariant", "id": "2720" }, { "type": "SmallVariant", "id": "2772" }, { "type": "SmallVariant", "id": "2818" }, { "type": "SmallVariant", "id": "2822" }, { "type": "SmallVariant", "id": "2823" }, { "type": "SmallVariant", "id": "2828" }, { "type": "SmallVariant", "id": "2837" }, { "type": "SmallVariant", "id": "2838" }, { "type": "SmallVariant", "id": "2841" }, { "type": "SmallVariant", "id": "2887" }, { "type": "SmallVariant", "id": "2932" }, { "type": "SmallVariant", "id": "2941" }, { "type": "SmallVariant", "id": "2945" }, { "type": "SmallVariant", "id": "2951" }, { "type": "SmallVariant", "id": "2952" }, { "type": "SmallVariant", "id": "2973" }, { "type": "SmallVariant", "id": "2986" }, { "type": "SmallVariant", "id": "3001" }, { "type": "SmallVariant", "id": "3005" }, { "type": "SmallVariant", "id": "3197" }, { "type": "SmallVariant", "id": "3223" }, { "type": "SmallVariant", "id": "3264" }, { "type": "SmallVariant", "id": "3321" }, { "type": "SmallVariant", "id": "3358" }, { "type": "SmallVariant", "id": "3359" }, { "type": "SmallVariant", "id": "3363" }, { "type": "SmallVariant", "id": "3376" }, { "type": "SmallVariant", "id": "3381" }, { "type": "SmallVariant", "id": "3384" }, { "type": "SmallVariant", "id": "3386" }, { "type": "SmallVariant", "id": "3472" }, { "type": "SmallVariant", "id": "3473" }, { "type": "SmallVariant", "id": "3475" }, { "type": "SmallVariant", "id": "3703" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CHD7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CHD7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 52 }, "data": [ { "type": "GeneCombination", "id": "16" }, { "type": "GeneCombination", "id": "98" }, { "type": "GeneCombination", "id": "227" }, { "type": "GeneCombination", "id": "242" }, { "type": "GeneCombination", "id": "371" }, { "type": "GeneCombination", "id": "387" }, { "type": "GeneCombination", "id": "478" }, { "type": "GeneCombination", "id": "618" }, { "type": "GeneCombination", "id": "627" }, { "type": "GeneCombination", "id": "634" }, { "type": "GeneCombination", "id": "636" }, { "type": "GeneCombination", "id": "639" }, { "type": "GeneCombination", "id": "643" }, { "type": "GeneCombination", "id": "661" }, { "type": "GeneCombination", "id": "666" }, { "type": "GeneCombination", "id": "675" }, { "type": "GeneCombination", "id": "891" }, { "type": "GeneCombination", "id": "718" }, { "type": "GeneCombination", "id": "819" }, { "type": "GeneCombination", "id": "845" }, { "type": "GeneCombination", "id": "847" }, { "type": "GeneCombination", "id": "818" }, { "type": "GeneCombination", "id": "885" }, { "type": "GeneCombination", "id": "606" }, { "type": "GeneCombination", "id": "888" }, { "type": "GeneCombination", "id": "892" }, { "type": "GeneCombination", "id": "899" }, { "type": "GeneCombination", "id": "312" }, { "type": "GeneCombination", "id": "846" }, { "type": "GeneCombination", "id": "939" }, { "type": "GeneCombination", "id": "941" }, { "type": "GeneCombination", "id": "944" }, { "type": "GeneCombination", "id": "945" }, { "type": "GeneCombination", "id": "949" }, { "type": "GeneCombination", "id": "956" }, { "type": "GeneCombination", "id": "974" }, { "type": "GeneCombination", "id": "978" }, { "type": "GeneCombination", "id": "980" }, { "type": "GeneCombination", "id": "982" }, { "type": "GeneCombination", "id": "990" }, { "type": "GeneCombination", "id": "1002" }, { "type": "GeneCombination", "id": "1003" }, { "type": "GeneCombination", "id": "1078" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1088" }, { "type": "GeneCombination", "id": "1097" }, { "type": "GeneCombination", "id": "1117" }, { "type": "GeneCombination", "id": "850" }, { "type": "GeneCombination", "id": "1165" }, { "type": "GeneCombination", "id": "1166" }, { "type": "GeneCombination", "id": "1167" }, { "type": "GeneCombination", "id": "1253" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CHD7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CHD7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CHD7/?format=api" } }, { "type": "Gene", "id": "MYRF", "attributes": { "go_molecular_function": [ "['DNA-binding transcription factor activity, RNA polymerase II-specific', 'sequence-specific DNA binding', 'DNA-binding transcription factor activity', 'peptidase activity']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9Y2G1", "ensembl_id": "None", "entrez_id": "ENSG00000124920", "chromosome_number": "11", "lastmodified": "2023-05-16T12:02:33.516815" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3166" }, { "type": "SmallVariant", "id": "3188" }, { "type": "SmallVariant", "id": "3310" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYRF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "1057" }, { "type": "GeneCombination", "id": "1060" }, { "type": "GeneCombination", "id": "1065" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1113" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MYRF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MYRF/?format=api" } }, { "type": "Gene", "id": "PROKR2", "attributes": { "go_molecular_function": [ "['neuropeptide Y receptor activity', 'protein binding', 'G protein-coupled receptor activity']" ], "pathway_id": [ "R-HSA-162582", "R-HSA-372790", "R-HSA-373076", "R-HSA-375276", "R-HSA-388396", "R-HSA-416476", "R-HSA-500792" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000101292", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.395103" }, "relationships": { "variant_set": { "meta": { "count": 38 }, "data": [ { "type": "SmallVariant", "id": "26" }, { "type": "SmallVariant", "id": "78" }, { "type": "SmallVariant", "id": "331" }, { "type": "SmallVariant", "id": "383" }, { "type": "SmallVariant", "id": "397" }, { "type": "SmallVariant", "id": "400" }, { "type": "SmallVariant", "id": "402" }, { "type": "SmallVariant", "id": "857" }, { "type": "SmallVariant", "id": "1057" }, { "type": "SmallVariant", "id": "1798" }, { "type": "SmallVariant", "id": "1825" }, { "type": "SmallVariant", "id": "1826" }, { "type": "SmallVariant", "id": "1857" }, { "type": "SmallVariant", "id": "1864" }, { "type": "SmallVariant", "id": "1888" }, { "type": "SmallVariant", "id": "1892" }, { "type": "SmallVariant", "id": "1898" }, { "type": "SmallVariant", "id": "1901" }, { "type": "SmallVariant", "id": "1931" }, { "type": "SmallVariant", "id": "2398" }, { "type": "SmallVariant", "id": "2399" }, { "type": "SmallVariant", "id": "2502" }, { "type": "SmallVariant", "id": "2513" }, { "type": "SmallVariant", "id": "2517" }, { "type": "SmallVariant", "id": "2577" }, { "type": "SmallVariant", "id": "2579" }, { "type": "SmallVariant", "id": "2662" }, { "type": "SmallVariant", "id": "2678" }, { "type": "SmallVariant", "id": "2691" }, { "type": "SmallVariant", "id": "2696" }, { "type": "SmallVariant", "id": "2699" }, { "type": "SmallVariant", "id": "2719" }, { "type": "SmallVariant", "id": "2721" }, { "type": "SmallVariant", "id": "2725" }, { "type": "SmallVariant", "id": "2768" }, { "type": "SmallVariant", "id": "2829" }, { "type": "SmallVariant", "id": "2831" }, { "type": "SmallVariant", "id": "3175" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PROKR2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 52 }, "data": [ { "type": "GeneCombination", "id": "10" }, { "type": "GeneCombination", "id": "31" }, { "type": "GeneCombination", "id": "116" }, { "type": "GeneCombination", "id": "265" }, { "type": "GeneCombination", "id": "257" }, { "type": "GeneCombination", "id": "442" }, { "type": "GeneCombination", "id": "478" }, { "type": "GeneCombination", "id": "596" }, { "type": "GeneCombination", "id": "616" }, { "type": "GeneCombination", "id": "617" }, { "type": "GeneCombination", "id": "619" }, { "type": "GeneCombination", "id": "622" }, { "type": "GeneCombination", "id": "626" }, { "type": "GeneCombination", "id": "629" }, { "type": "GeneCombination", "id": "630" }, { "type": "GeneCombination", "id": "631" }, { "type": "GeneCombination", "id": "632" }, { "type": "GeneCombination", "id": "637" }, { "type": "GeneCombination", "id": "653" }, { "type": "GeneCombination", "id": "656" }, { "type": "GeneCombination", "id": "662" }, { "type": "GeneCombination", "id": "663" }, { "type": "GeneCombination", "id": "817" }, { "type": "GeneCombination", "id": "852" }, { "type": "GeneCombination", "id": "854" }, { "type": "GeneCombination", "id": "859" }, { "type": "GeneCombination", "id": "606" }, { "type": "GeneCombination", "id": "189" }, { "type": "GeneCombination", "id": "858" }, { "type": "GeneCombination", "id": "892" }, { "type": "GeneCombination", "id": "896" }, { "type": "GeneCombination", "id": "898" }, { "type": "GeneCombination", "id": "136" }, { "type": "GeneCombination", "id": "902" }, { "type": "GeneCombination", "id": "903" }, { "type": "GeneCombination", "id": "904" }, { "type": "GeneCombination", "id": "906" }, { "type": "GeneCombination", "id": "910" }, { "type": "GeneCombination", "id": "90" }, { "type": "GeneCombination", "id": "941" }, { "type": "GeneCombination", "id": "635" }, { "type": "GeneCombination", "id": "947" }, { "type": "GeneCombination", "id": "971" }, { "type": "GeneCombination", "id": "1061" }, { "type": "GeneCombination", "id": "1069" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1084" }, { "type": "GeneCombination", "id": "1088" }, { "type": "GeneCombination", "id": "1091" }, { "type": "GeneCombination", "id": "1092" }, { "type": "GeneCombination", "id": "1102" }, { "type": "GeneCombination", "id": "1111" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PROKR2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }