Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/971/genes/?format=api
{ "data": [ { "type": "Gene", "id": "FGFR1", "attributes": { "go_molecular_function": [ "['identical protein binding', 'protein tyrosine kinase activity', 'ATP binding', 'fibroblast growth factor binding', 'receptor-receptor interaction', 'protein binding', 'heparin binding', 'protein homodimerization activity', 'protein serine/threonine/tyrosine kinase activity', 'fibroblast growth factor-activated receptor activity', 'transmembrane receptor protein tyrosine kinase activity']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04014", "kegg_path:hsa04015", "kegg_path:hsa04020", "kegg_path:hsa04151", "kegg_path:hsa04520", "kegg_path:hsa04550", "kegg_path:hsa04714", "kegg_path:hsa04810", "kegg_path:hsa04928", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05215", "kegg_path:hsa05218", "kegg_path:hsa05224", "kegg_path:hsa05230", "R-HSA-1226099", "R-HSA-1643685", "R-HSA-1839122", "R-HSA-1839124", "R-HSA-5655302", "R-HSA-5663202", "R-HSA-8853336" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P11362", "ensembl_id": "None", "entrez_id": "ENSG00000077782", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.319679" }, "relationships": { "variant_set": { "meta": { "count": 92 }, "data": [ { "type": "SmallVariant", "id": "1973" }, { "type": "SmallVariant", "id": "2820" }, { "type": "SmallVariant", "id": "37" }, { "type": "SmallVariant", "id": "77" }, { "type": "SmallVariant", "id": "147" }, { "type": "SmallVariant", "id": "379" }, { "type": "SmallVariant", "id": "382" }, { "type": "SmallVariant", "id": "384" }, { "type": "SmallVariant", "id": "386" }, { "type": "SmallVariant", "id": "388" }, { "type": "SmallVariant", "id": "398" }, { "type": "SmallVariant", "id": "557" }, { "type": "SmallVariant", "id": "779" }, { "type": "SmallVariant", "id": "801" }, { "type": "SmallVariant", "id": "809" }, { "type": "SmallVariant", "id": "813" }, { "type": "SmallVariant", "id": "814" }, { "type": "SmallVariant", "id": "817" }, { "type": "SmallVariant", "id": "818" }, { "type": "SmallVariant", "id": "820" }, { "type": "SmallVariant", "id": "844" }, { "type": "SmallVariant", "id": "846" }, { "type": "SmallVariant", "id": "848" }, { "type": "SmallVariant", "id": "850" }, { "type": "SmallVariant", "id": "858" }, { "type": "SmallVariant", "id": "879" }, { "type": "SmallVariant", "id": "881" }, { "type": "SmallVariant", "id": "899" }, { "type": "SmallVariant", "id": "901" }, { "type": "SmallVariant", "id": "972" }, { "type": "SmallVariant", "id": "1156" }, { "type": "SmallVariant", "id": "1419" }, { "type": "SmallVariant", "id": "1494" }, { "type": "SmallVariant", "id": "1714" }, { "type": "SmallVariant", "id": "1824" }, { "type": "SmallVariant", "id": "1828" }, { "type": "SmallVariant", "id": "1846" }, { "type": "SmallVariant", "id": "1878" }, { "type": "SmallVariant", "id": "1943" }, { "type": "SmallVariant", "id": "1963" }, { "type": "SmallVariant", "id": "2344" }, { "type": "SmallVariant", "id": "2393" }, { "type": "SmallVariant", "id": "2394" }, { "type": "SmallVariant", "id": "2396" }, { "type": "SmallVariant", "id": "2492" }, { "type": "SmallVariant", "id": "2497" }, { "type": "SmallVariant", "id": "2672" }, { "type": "SmallVariant", "id": "2675" }, { "type": "SmallVariant", "id": "2677" }, { "type": "SmallVariant", "id": "2681" }, { "type": "SmallVariant", "id": "2683" }, { "type": "SmallVariant", "id": "2684" }, { "type": "SmallVariant", "id": "2687" }, { "type": "SmallVariant", "id": "2707" }, { "type": "SmallVariant", "id": "2713" }, { "type": "SmallVariant", "id": "2723" }, { "type": "SmallVariant", "id": "2732" }, { "type": "SmallVariant", "id": "2771" }, { "type": "SmallVariant", "id": "2825" }, { "type": "SmallVariant", "id": "2826" }, { "type": "SmallVariant", "id": "2842" }, { "type": "SmallVariant", "id": "2844" }, { "type": "SmallVariant", "id": "2846" }, { "type": "SmallVariant", "id": "2853" }, { "type": "SmallVariant", "id": "2854" }, { "type": "SmallVariant", "id": "2883" }, { "type": "SmallVariant", "id": "2891" }, { "type": "SmallVariant", "id": "2893" }, { "type": "SmallVariant", "id": "2895" }, { "type": "SmallVariant", "id": "2924" }, { "type": "SmallVariant", "id": "2931" }, { "type": "SmallVariant", "id": "2935" }, { "type": "SmallVariant", "id": "2943" }, { "type": "SmallVariant", "id": "2946" }, { "type": "SmallVariant", "id": "2959" }, { "type": "SmallVariant", "id": "2964" }, { "type": "SmallVariant", "id": "2971" }, { "type": "SmallVariant", "id": "2984" }, { "type": "SmallVariant", "id": "2990" }, { "type": "SmallVariant", "id": "2991" }, { "type": "SmallVariant", "id": "3006" }, { "type": "SmallVariant", "id": "3008" }, { "type": "SmallVariant", "id": "3011" }, { "type": "SmallVariant", "id": "3191" }, { "type": "SmallVariant", "id": "3278" }, { "type": "SmallVariant", "id": "3293" }, { "type": "SmallVariant", "id": "3361" }, { "type": "SmallVariant", "id": "3362" }, { "type": "SmallVariant", "id": "3372" }, { "type": "SmallVariant", "id": "3378" }, { "type": "SmallVariant", "id": "3380" }, { "type": "SmallVariant", "id": "3385" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FGFR1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FGFR1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 57 }, "data": [ { "type": "GeneCombination", "id": "31" }, { "type": "GeneCombination", "id": "15" }, { "type": "GeneCombination", "id": "131" }, { "type": "GeneCombination", "id": "252" }, { "type": "GeneCombination", "id": "253" }, { "type": "GeneCombination", "id": "257" }, { "type": "GeneCombination", "id": "259" }, { "type": "GeneCombination", "id": "258" }, { "type": "GeneCombination", "id": "261" }, { "type": "GeneCombination", "id": "255" }, { "type": "GeneCombination", "id": "279" }, { "type": "GeneCombination", "id": "370" }, { "type": "GeneCombination", "id": "446" }, { "type": "GeneCombination", "id": "478" }, { "type": "GeneCombination", "id": "613" }, { "type": "GeneCombination", "id": "625" }, { "type": "GeneCombination", "id": "672" }, { "type": "GeneCombination", "id": "891" }, { "type": "GeneCombination", "id": "792" }, { "type": "GeneCombination", "id": "815" }, { "type": "GeneCombination", "id": "816" }, { "type": "GeneCombination", "id": "844" }, { "type": "GeneCombination", "id": "890" }, { "type": "GeneCombination", "id": "256" }, { "type": "GeneCombination", "id": "130" }, { "type": "GeneCombination", "id": "893" }, { "type": "GeneCombination", "id": "53" }, { "type": "GeneCombination", "id": "905" }, { "type": "GeneCombination", "id": "846" }, { "type": "GeneCombination", "id": "940" }, { "type": "GeneCombination", "id": "946" }, { "type": "GeneCombination", "id": "260" }, { "type": "GeneCombination", "id": "954" }, { "type": "GeneCombination", "id": "958" }, { "type": "GeneCombination", "id": "959" }, { "type": "GeneCombination", "id": "960" }, { "type": "GeneCombination", "id": "970" }, { "type": "GeneCombination", "id": "971" }, { "type": "GeneCombination", "id": "972" }, { "type": "GeneCombination", "id": "976" }, { "type": "GeneCombination", "id": "979" }, { "type": "GeneCombination", "id": "980" }, { "type": "GeneCombination", "id": "985" }, { "type": "GeneCombination", "id": "987" }, { "type": "GeneCombination", "id": "990" }, { "type": "GeneCombination", "id": "996" }, { "type": "GeneCombination", "id": "999" }, { "type": "GeneCombination", "id": "280" }, { "type": "GeneCombination", "id": "1004" }, { "type": "GeneCombination", "id": "1005" }, { "type": "GeneCombination", "id": "1066" }, { "type": "GeneCombination", "id": "1103" }, { "type": "GeneCombination", "id": "1108" }, { "type": "GeneCombination", "id": "244" }, { "type": "GeneCombination", "id": "1130" }, { "type": "GeneCombination", "id": "1131" }, { "type": "GeneCombination", "id": "678" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FGFR1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FGFR1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FGFR1/?format=api" } }, { "type": "Gene", "id": "OTUD4", "attributes": { "go_molecular_function": [ "['RNA binding', 'molecular adaptor activity', 'protein binding', 'Lys63-specific deubiquitinase activity', 'thiol-dependent deubiquitinase']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q01804", "ensembl_id": "None", "entrez_id": "ENSG00000164164", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.654507" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "3009" }, { "type": "SmallVariant", "id": "587" }, { "type": "SmallVariant", "id": "2925" }, { "type": "SmallVariant", "id": "2975" }, { "type": "SmallVariant", "id": "3010" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/OTUD4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/OTUD4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "203" }, { "type": "GeneCombination", "id": "971" }, { "type": "GeneCombination", "id": "991" }, { "type": "GeneCombination", "id": "1004" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/OTUD4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/OTUD4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/OTUD4/?format=api" } }, { "type": "Gene", "id": "PROKR2", "attributes": { "go_molecular_function": [ "['neuropeptide Y receptor activity', 'protein binding', 'G protein-coupled receptor activity']" ], "pathway_id": [ "R-HSA-162582", "R-HSA-372790", "R-HSA-373076", "R-HSA-375276", "R-HSA-388396", "R-HSA-416476", "R-HSA-500792" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000101292", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.395103" }, "relationships": { "variant_set": { "meta": { "count": 38 }, "data": [ { "type": "SmallVariant", "id": "26" }, { "type": "SmallVariant", "id": "78" }, { "type": "SmallVariant", "id": "331" }, { "type": "SmallVariant", "id": "383" }, { "type": "SmallVariant", "id": "397" }, { "type": "SmallVariant", "id": "400" }, { "type": "SmallVariant", "id": "402" }, { "type": "SmallVariant", "id": "857" }, { "type": "SmallVariant", "id": "1057" }, { "type": "SmallVariant", "id": "1798" }, { "type": "SmallVariant", "id": "1825" }, { "type": "SmallVariant", "id": "1826" }, { "type": "SmallVariant", "id": "1857" }, { "type": "SmallVariant", "id": "1864" }, { "type": "SmallVariant", "id": "1888" }, { "type": "SmallVariant", "id": "1892" }, { "type": "SmallVariant", "id": "1898" }, { "type": "SmallVariant", "id": "1901" }, { "type": "SmallVariant", "id": "1931" }, { "type": "SmallVariant", "id": "2398" }, { "type": "SmallVariant", "id": "2399" }, { "type": "SmallVariant", "id": "2502" }, { "type": "SmallVariant", "id": "2513" }, { "type": "SmallVariant", "id": "2517" }, { "type": "SmallVariant", "id": "2577" }, { "type": "SmallVariant", "id": "2579" }, { "type": "SmallVariant", "id": "2662" }, { "type": "SmallVariant", "id": "2678" }, { "type": "SmallVariant", "id": "2691" }, { "type": "SmallVariant", "id": "2696" }, { "type": "SmallVariant", "id": "2699" }, { "type": "SmallVariant", "id": "2719" }, { "type": "SmallVariant", "id": "2721" }, { "type": "SmallVariant", "id": "2725" }, { "type": "SmallVariant", "id": "2768" }, { "type": "SmallVariant", "id": "2829" }, { "type": "SmallVariant", "id": "2831" }, { "type": "SmallVariant", "id": "3175" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PROKR2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 52 }, "data": [ { "type": "GeneCombination", "id": "10" }, { "type": "GeneCombination", "id": "31" }, { "type": "GeneCombination", "id": "116" }, { "type": "GeneCombination", "id": "265" }, { "type": "GeneCombination", "id": "257" }, { "type": "GeneCombination", "id": "442" }, { "type": "GeneCombination", "id": "478" }, { "type": "GeneCombination", "id": "596" }, { "type": "GeneCombination", "id": "616" }, { "type": "GeneCombination", "id": "617" }, { "type": "GeneCombination", "id": "619" }, { "type": "GeneCombination", "id": "622" }, { "type": "GeneCombination", "id": "626" }, { "type": "GeneCombination", "id": "629" }, { "type": "GeneCombination", "id": "630" }, { "type": "GeneCombination", "id": "631" }, { "type": "GeneCombination", "id": "632" }, { "type": "GeneCombination", "id": "637" }, { "type": "GeneCombination", "id": "653" }, { "type": "GeneCombination", "id": "656" }, { "type": "GeneCombination", "id": "662" }, { "type": "GeneCombination", "id": "663" }, { "type": "GeneCombination", "id": "817" }, { "type": "GeneCombination", "id": "852" }, { "type": "GeneCombination", "id": "854" }, { "type": "GeneCombination", "id": "859" }, { "type": "GeneCombination", "id": "606" }, { "type": "GeneCombination", "id": "189" }, { "type": "GeneCombination", "id": "858" }, { "type": "GeneCombination", "id": "892" }, { "type": "GeneCombination", "id": "896" }, { "type": "GeneCombination", "id": "898" }, { "type": "GeneCombination", "id": "136" }, { "type": "GeneCombination", "id": "902" }, { "type": "GeneCombination", "id": "903" }, { "type": "GeneCombination", "id": "904" }, { "type": "GeneCombination", "id": "906" }, { "type": "GeneCombination", "id": "910" }, { "type": "GeneCombination", "id": "90" }, { "type": "GeneCombination", "id": "941" }, { "type": "GeneCombination", "id": "635" }, { "type": "GeneCombination", "id": "947" }, { "type": "GeneCombination", "id": "971" }, { "type": "GeneCombination", "id": "1061" }, { "type": "GeneCombination", "id": "1069" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1084" }, { "type": "GeneCombination", "id": "1088" }, { "type": "GeneCombination", "id": "1091" }, { "type": "GeneCombination", "id": "1092" }, { "type": "GeneCombination", "id": "1102" }, { "type": "GeneCombination", "id": "1111" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PROKR2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }