Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/622/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DCC", "attributes": { "go_molecular_function": [ "['transmembrane signaling receptor activity', 'protein binding', 'netrin receptor activity']" ], "pathway_id": [ "kegg_path:hsa04360", "kegg_path:hsa05200", "kegg_path:hsa05210", "R-HSA-109581", "R-HSA-1266738", "R-HSA-373752", "R-HSA-376172", "R-HSA-376176", "R-HSA-418885", "R-HSA-418886", "R-HSA-418889", "R-HSA-418890", "R-HSA-422475", "R-HSA-428542", "R-HSA-5357769", "R-HSA-5357801", "R-HSA-9675108", "kegg_path:hsa04360", "kegg_path:hsa05200", "kegg_path:hsa05210" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P43146", "ensembl_id": "None", "entrez_id": "ENSG00000187323", "chromosome_number": "18", "lastmodified": "2021-10-18T11:00:44.731182" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "1847" }, { "type": "SmallVariant", "id": "1872" }, { "type": "SmallVariant", "id": "1907" }, { "type": "SmallVariant", "id": "1955" }, { "type": "SmallVariant", "id": "2884" }, { "type": "SmallVariant", "id": "2949" }, { "type": "SmallVariant", "id": "2989" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DCC/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DCC/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "613" }, { "type": "GeneCombination", "id": "622" }, { "type": "GeneCombination", "id": "640" }, { "type": "GeneCombination", "id": "667" }, { "type": "GeneCombination", "id": "954" }, { "type": "GeneCombination", "id": "981" }, { "type": "GeneCombination", "id": "998" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DCC/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DCC/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DCC/?format=api" } }, { "type": "Gene", "id": "MET", "attributes": { "go_molecular_function": [ "protein tyrosine kinase activity", "protein binding" ], "pathway_id": [ "kegg_path:hsa05226", "R-HSA-8851805", "R-HSA-2219530", "kegg_path:hsa05202", "kegg_path:hsa01521", "kegg_path:hsa05206", "kegg_path:hsa05211", "kegg_path:hsa05100", "R-HSA-9006934", "kegg_path:hsa04015", "R-HSA-199418", "R-HSA-5663202", "kegg_path:hsa05200", "kegg_path:hsa04010", "kegg_path:hsa05223", "R-HSA-5684996", "R-HSA-8874081", "R-HSA-8875555", "R-HSA-162582", "kegg_path:hsa04020", "R-HSA-8865999", "kegg_path:hsa04014", "R-HSA-1266738", "kegg_path:hsa05205", "R-HSA-5663205", "R-HSA-8876384", "R-HSA-6807004", "kegg_path:hsa05202", "R-HSA-2219528", "R-HSA-400685", "R-HSA-8851907", "kegg_path:hsa01521", "kegg_path:hsa05206", "kegg_path:hsa05230", "kegg_path:hsa05211", "kegg_path:hsa05225", "kegg_path:hsa04151", "kegg_path:hsa04360", "kegg_path:hsa05226", "kegg_path:hsa05120", "kegg_path:hsa04510", "R-HSA-73857", "R-HSA-8986944", "R-HSA-9022699", "kegg_path:hsa04015", "R-HSA-8875513", "kegg_path:hsa04520", "kegg_path:hsa05100", "kegg_path:hsa05218", "kegg_path:hsa04010", "kegg_path:hsa05223", "R-HSA-5673001", "R-HSA-416550", "kegg_path:hsa04020", "R-HSA-8875878", "R-HSA-6806942", "kegg_path:hsa05144", "R-HSA-8875656", "R-HSA-9006925", "kegg_path:hsa05200", "R-HSA-1257604", "R-HSA-8875360", "kegg_path:hsa05205", "R-HSA-8875791", "R-HSA-212436", "R-HSA-6811558", "R-HSA-422475", "kegg_path:hsa04014", "R-HSA-5683057", "R-HSA-9675108", "kegg_path:hsa04151", "kegg_path:hsa04360", "R-HSA-1643685", "kegg_path:hsa04510", "kegg_path:hsa05120", "kegg_path:hsa05230", "kegg_path:hsa05225", "kegg_path:hsa04520", "kegg_path:hsa05218", "R-HSA-6806834", "R-HSA-373755", "R-HSA-74160", "kegg_path:hsa05144" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P08581", "ensembl_id": "ENSG00000105976", "entrez_id": "4233", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.557330" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1062" }, { "type": "SmallVariant", "id": "1873" }, { "type": "SmallVariant", "id": "1958" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MET/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MET/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "346" }, { "type": "GeneCombination", "id": "622" }, { "type": "GeneCombination", "id": "669" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MET/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MET/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MET/?format=api" } }, { "type": "Gene", "id": "PROKR2", "attributes": { "go_molecular_function": [ "['neuropeptide Y receptor activity', 'protein binding', 'G protein-coupled receptor activity']" ], "pathway_id": [ "R-HSA-162582", "R-HSA-372790", "R-HSA-373076", "R-HSA-375276", "R-HSA-388396", "R-HSA-416476", "R-HSA-500792" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000101292", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.395103" }, "relationships": { "variant_set": { "meta": { "count": 38 }, "data": [ { "type": "SmallVariant", "id": "26" }, { "type": "SmallVariant", "id": "78" }, { "type": "SmallVariant", "id": "331" }, { "type": "SmallVariant", "id": "383" }, { "type": "SmallVariant", "id": "397" }, { "type": "SmallVariant", "id": "400" }, { "type": "SmallVariant", "id": "402" }, { "type": "SmallVariant", "id": "857" }, { "type": "SmallVariant", "id": "1057" }, { "type": "SmallVariant", "id": "1798" }, { "type": "SmallVariant", "id": "1825" }, { "type": "SmallVariant", "id": "1826" }, { "type": "SmallVariant", "id": "1857" }, { "type": "SmallVariant", "id": "1864" }, { "type": "SmallVariant", "id": "1888" }, { "type": "SmallVariant", "id": "1892" }, { "type": "SmallVariant", "id": "1898" }, { "type": "SmallVariant", "id": "1901" }, { "type": "SmallVariant", "id": "1931" }, { "type": "SmallVariant", "id": "2398" }, { "type": "SmallVariant", "id": "2399" }, { "type": "SmallVariant", "id": "2502" }, { "type": "SmallVariant", "id": "2513" }, { "type": "SmallVariant", "id": "2517" }, { "type": "SmallVariant", "id": "2577" }, { "type": "SmallVariant", "id": "2579" }, { "type": "SmallVariant", "id": "2662" }, { "type": "SmallVariant", "id": "2678" }, { "type": "SmallVariant", "id": "2691" }, { "type": "SmallVariant", "id": "2696" }, { "type": "SmallVariant", "id": "2699" }, { "type": "SmallVariant", "id": "2719" }, { "type": "SmallVariant", "id": "2721" }, { "type": "SmallVariant", "id": "2725" }, { "type": "SmallVariant", "id": "2768" }, { "type": "SmallVariant", "id": "2829" }, { "type": "SmallVariant", "id": "2831" }, { "type": "SmallVariant", "id": "3175" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PROKR2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 52 }, "data": [ { "type": "GeneCombination", "id": "10" }, { "type": "GeneCombination", "id": "31" }, { "type": "GeneCombination", "id": "116" }, { "type": "GeneCombination", "id": "265" }, { "type": "GeneCombination", "id": "257" }, { "type": "GeneCombination", "id": "442" }, { "type": "GeneCombination", "id": "478" }, { "type": "GeneCombination", "id": "596" }, { "type": "GeneCombination", "id": "616" }, { "type": "GeneCombination", "id": "617" }, { "type": "GeneCombination", "id": "619" }, { "type": "GeneCombination", "id": "622" }, { "type": "GeneCombination", "id": "626" }, { "type": "GeneCombination", "id": "629" }, { "type": "GeneCombination", "id": "630" }, { "type": "GeneCombination", "id": "631" }, { "type": "GeneCombination", "id": "632" }, { "type": "GeneCombination", "id": "637" }, { "type": "GeneCombination", "id": "653" }, { "type": "GeneCombination", "id": "656" }, { "type": "GeneCombination", "id": "662" }, { "type": "GeneCombination", "id": "663" }, { "type": "GeneCombination", "id": "817" }, { "type": "GeneCombination", "id": "852" }, { "type": "GeneCombination", "id": "854" }, { "type": "GeneCombination", "id": "859" }, { "type": "GeneCombination", "id": "606" }, { "type": "GeneCombination", "id": "189" }, { "type": "GeneCombination", "id": "858" }, { "type": "GeneCombination", "id": "892" }, { "type": "GeneCombination", "id": "896" }, { "type": "GeneCombination", "id": "898" }, { "type": "GeneCombination", "id": "136" }, { "type": "GeneCombination", "id": "902" }, { "type": "GeneCombination", "id": "903" }, { "type": "GeneCombination", "id": "904" }, { "type": "GeneCombination", "id": "906" }, { "type": "GeneCombination", "id": "910" }, { "type": "GeneCombination", "id": "90" }, { "type": "GeneCombination", "id": "941" }, { "type": "GeneCombination", "id": "635" }, { "type": "GeneCombination", "id": "947" }, { "type": "GeneCombination", "id": "971" }, { "type": "GeneCombination", "id": "1061" }, { "type": "GeneCombination", "id": "1069" }, { "type": "GeneCombination", "id": "1080" }, { "type": "GeneCombination", "id": "1084" }, { "type": "GeneCombination", "id": "1088" }, { "type": "GeneCombination", "id": "1091" }, { "type": "GeneCombination", "id": "1092" }, { "type": "GeneCombination", "id": "1102" }, { "type": "GeneCombination", "id": "1111" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PROKR2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PROKR2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }