Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/genecombinations/606/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI836", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 1, "final_metascore": 1 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2023-05-16T12:33:32.379959" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI836/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI836/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1826" }, { "type": "SmallVariant", "id": "1830" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI836/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI836/variants/?format=api" } }, "reference_set": { "meta": { "count": 2 }, "data": [ { "type": "Reference", "id": "858" }, { "type": "Reference", "id": "948" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI836/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI836/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI836/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI836/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "606" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI836/?format=api" } }, { "type": "Combination", "id": "OLI1261", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM612702", "OMIM614841", "OMIM606394", "OMIM615270", "OMIM147950", "OMIM616511", "OMIM614840", "OMIM612370", "OMIM610508", "OMIM308700", "OMIM609812", "OMIM612225", "OMIM613370", "OMIM616329", "OMIM610628", "OMIM614858", "OMIM125851", "OMIM606392", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM125850", "OMIM244200", "OMIM613375", "OMIM614842", "OMIM600496", "OMIM606391", "OMIM614839", "OMIM615269", "OMIM146110" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:43.311283" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "432" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1261/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1261/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2661" }, { "type": "SmallVariant", "id": "2662" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1261/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1261/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "937" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1261/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1261/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1261/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1261/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "606" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1261/?format=api" } }, { "type": "Combination", "id": "OLI1276", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM612702", "OMIM614841", "OMIM606394", "OMIM615270", "OMIM147950", "OMIM616511", "OMIM614840", "OMIM612370", "OMIM610508", "OMIM308700", "OMIM609812", "OMIM612225", "OMIM613370", "OMIM616329", "OMIM610628", "OMIM614858", "OMIM125851", "OMIM606392", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM125850", "OMIM244200", "OMIM613375", "OMIM614842", "OMIM600496", "OMIM606391", "OMIM614839", "OMIM615269", "OMIM146110" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:44.298302" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "432" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1276/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1276/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2691" }, { "type": "SmallVariant", "id": "2661" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1276/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1276/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "937" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1276/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1276/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1276/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1276/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "606" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1276/?format=api" } }, { "type": "Combination", "id": "OLI1294", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:45.419342" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1294/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1294/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2719" }, { "type": "SmallVariant", "id": "2720" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1294/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1294/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "937" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1294/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1294/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1294/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1294/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "606" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1294/?format=api" } }, { "type": "Combination", "id": "OLI847", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 2, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 2, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM614897", "OMIM612702", "OMIM615270", "OMIM147950", "OMIM614840", "OMIM612370", "OMIM308700", "OMIM610628", "OMIM614858", "OMIM614837", "OMIM614838", "OMIM614880", "OMIM615266", "OMIM615267", "OMIM244200", "OMIM615271", "OMIM616030", "OMIM615269", "OMIM618841" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2023-05-16T12:34:16.572845" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI847/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI847/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1826" }, { "type": "SmallVariant", "id": "1853" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI847/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI847/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "866" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI847/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI847/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI847/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI847/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "606" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI847/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 5 } }