Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/AR/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "200", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.784938" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI299" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/200/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/200/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "HOXB6" }, { "type": "Gene", "id": "MAMLD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/200/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/200/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/200/?format=api" } }, { "type": "GeneCombination", "id": "217", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Metabolic pathways", "Signaling by Interleukins", "Immune System", "Pathways in cancer", "Metabolism of proteins", "Post-translational protein modification", "Cytokine Signaling in Immune system", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:55.857615" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI329" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/217/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "ALOX15" }, { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "COL4A1" }, { "type": "Gene", "id": "FBXW8" }, { "type": "Gene", "id": "NOB1" }, { "type": "Gene", "id": "PMM2" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "TPP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/217/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/217/?format=api" } }, { "type": "GeneCombination", "id": "736", "attributes": { "gene_relationship": [ "Directly interacting" ], "protein_interactions": [ "(AR, FKBP4)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.386335" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI996" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/736/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/736/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "DGKK" }, { "type": "Gene", "id": "EGF" }, { "type": "Gene", "id": "FKBP4" }, { "type": "Gene", "id": "GJA4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/736/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/736/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/736/?format=api" } }, { "type": "GeneCombination", "id": "737", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.443346" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI997" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/737/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/737/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "BMP4" }, { "type": "Gene", "id": "MAP3K1" }, { "type": "Gene", "id": "POR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/737/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/737/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/737/?format=api" } }, { "type": "GeneCombination", "id": "738", "attributes": { "gene_relationship": [ "Directly interacting" ], "protein_interactions": [ "(AR, NR5A1)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.490973" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI998" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/738/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/738/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "MYH6" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/738/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/738/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/738/?format=api" } }, { "type": "GeneCombination", "id": "739", "attributes": { "gene_relationship": [ "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Prostate cancer" ], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.530655" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI999" }, { "type": "Combination", "id": "OLI1003" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/739/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/739/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "SRD5A2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/739/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/739/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/739/?format=api" } }, { "type": "GeneCombination", "id": "740", "attributes": { "gene_relationship": [ "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Cellular responses to external stimuli", "Generic Transcription Pathway", "Metabolism of proteins", "Signal Transduction", "Gene expression (Transcription)", "Cellular responses to stress", "SUMO E3 ligases SUMOylate target proteins", "RNA Polymerase II Transcription", "Post-translational protein modification", "SUMOylation" ], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.555716" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1000" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/740/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/740/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "CBX2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/740/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/740/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/740/?format=api" } }, { "type": "GeneCombination", "id": "741", "attributes": { "gene_relationship": [ "Same pathway", "Directly interacting" ], "protein_interactions": [ "(AR, ESR1)" ], "common_pathways": [ "Nuclear Receptor transcription pathway", "SUMOylation of intracellular receptors", "Generic Transcription Pathway", "Metabolism of proteins", "Signal Transduction", "Gene expression (Transcription)", "SUMO E3 ligases SUMOylate target proteins", "Post-translational protein modification", "RNA Polymerase II Transcription", "Transcriptional regulation by RUNX2", "Deubiquitination", "SUMOylation", "Pathways in cancer" ], "genecomb_metascore": 2, "lastmodified": "2022-08-04T14:15:02.580910" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1001" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/741/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/741/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "ESR1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/741/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/741/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/741/?format=api" } }, { "type": "GeneCombination", "id": "742", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.607668" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1002" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/742/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/742/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "GJA4" }, { "type": "Gene", "id": "POR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/742/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/742/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/742/?format=api" } }, { "type": "GeneCombination", "id": "743", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.647872" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1004" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/743/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/743/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "BMP7" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/743/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/743/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/743/?format=api" } }, { "type": "GeneCombination", "id": "744", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.672715" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1005" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/744/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/744/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "PHF6" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/744/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/744/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/744/?format=api" } }, { "type": "GeneCombination", "id": "745", "attributes": { "gene_relationship": [ "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Generic Transcription Pathway", "Gene expression (Transcription)", "Transcriptional regulation by RUNX2", "Signal Transduction", "RNA Polymerase II Transcription", "Pathways in cancer" ], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.697694" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1006" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/745/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/745/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "BMP2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/745/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/745/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/745/?format=api" } }, { "type": "GeneCombination", "id": "1089", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.132785" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1545" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1089/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1089/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "GHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1089/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1089/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1089/?format=api" } }, { "type": "GeneCombination", "id": "1108", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways in cancer", "Prostate cancer" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.302547" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1564" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1108/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1108/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "FGFR1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1108/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1108/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1108/?format=api" } }, { "type": "GeneCombination", "id": "1114", "attributes": { "gene_relationship": [], "protein_interactions": [ "(AR, FLNA)" ], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.369468" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1570" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1114/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1114/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "GPRC6A" }, { "type": "Gene", "id": "ROR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1114/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1114/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1114/?format=api" } } ] }