Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/741/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "741",
        "attributes": {
            "gene_relationship": [
                "Same pathway",
                "Directly interacting"
            ],
            "protein_interactions": [
                "(AR, ESR1)"
            ],
            "common_pathways": [
                "Nuclear Receptor transcription pathway",
                "SUMOylation of intracellular receptors",
                "Generic Transcription Pathway",
                "Metabolism of proteins",
                "Signal Transduction",
                "Gene expression (Transcription)",
                "SUMO E3 ligases SUMOylate target proteins",
                "Post-translational protein modification",
                "RNA Polymerase II Transcription",
                "Transcriptional regulation by RUNX2",
                "Deubiquitination",
                "SUMOylation",
                "Pathways in cancer"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2022-08-04T14:15:02.580910"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI1001"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/741/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/741/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "AR"
                    },
                    {
                        "type": "Gene",
                        "id": "ESR1"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/741/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/741/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/741/?format=api"
        }
    }
}