Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/FLNA/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "240", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(CDH23, MYO7A)", "(MAML2, NOTCH2)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.806836" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI352" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/240/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/240/combinations/?format=api" } }, "genes": { "meta": { "count": 10 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "EVC" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "MAML2" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "NOTCH2" }, { "type": "Gene", "id": "PIK3R3" }, { "type": "Gene", "id": "PTPN11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/240/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/240/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/240/?format=api" } }, { "type": "GeneCombination", "id": "410", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(CYP1A1, PTPN11)", "(FLNA, NRP1)", "(MAML1, MAML3)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.207559" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI602" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/410/combinations/?format=api" } }, "genes": { "meta": { "count": 17 }, "data": [ { "type": "Gene", "id": "BNC2" }, { "type": "Gene", "id": "NRP1" }, { "type": "Gene", "id": "PROP1" }, { "type": "Gene", "id": "PTPN11" }, { "type": "Gene", "id": "MAML1" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "IRX5" }, { "type": "Gene", "id": "ATF3" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "IRX6" }, { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "HOXA13" }, { "type": "Gene", "id": "WDR11" }, { "type": "Gene", "id": "EYA1" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "MAMLD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/410/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/?format=api" } }, { "type": "GeneCombination", "id": "1061", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.927151" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1516" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1061/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1061/combinations/?format=api" } }, "genes": { "meta": { "count": 7 }, "data": [ { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "NIPBL" }, { "type": "Gene", "id": "PLXNA3" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "SLC29A3" }, { "type": "Gene", "id": "SOX8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1061/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1061/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1061/?format=api" } }, { "type": "GeneCombination", "id": "1086", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.108124" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1542" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1086/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1086/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "LZTR1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1086/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1086/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1086/?format=api" } }, { "type": "GeneCombination", "id": "1102", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.248009" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1558" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1102/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1102/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "FGFR3" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "GLI2" }, { "type": "Gene", "id": "GPRC6A" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1102/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1102/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1102/?format=api" } }, { "type": "GeneCombination", "id": "1114", "attributes": { "gene_relationship": [], "protein_interactions": [ "(AR, FLNA)" ], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.369468" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1570" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1114/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1114/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "GPRC6A" }, { "type": "Gene", "id": "ROR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1114/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1114/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1114/?format=api" } } ] }