Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/FLNA/?format=api
{ "data": { "type": "Gene", "id": "FLNA", "attributes": { "go_molecular_function": [ "['RNA binding', 'Fc-gamma receptor I complex binding', 'small GTPase binding', 'actin filament binding', 'protein kinase C binding', 'transmembrane transporter binding', 'cadherin binding', 'potassium channel regulator activity', 'kinase binding', 'G protein-coupled receptor binding', 'protein binding', 'GTPase binding', 'protein homodimerization activity', 'DNA-binding transcription factor binding']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04510", "kegg_path:hsa05132", "kegg_path:hsa05205", "R-HSA-109582", "R-HSA-114608", "R-HSA-1169410", "R-HSA-1280215", "R-HSA-1500931", "R-HSA-162582", "R-HSA-168256", "R-HSA-194315", "R-HSA-195258", "R-HSA-430116", "R-HSA-446353", "R-HSA-446728", "R-HSA-5627123", "R-HSA-76002", "R-HSA-76005", "R-HSA-8983711", "R-HSA-913531", "kegg_path:hsa04010", "kegg_path:hsa04510", "kegg_path:hsa05132", "kegg_path:hsa05205", "kegg_path:hsa04010", "kegg_path:hsa04510", "kegg_path:hsa05132", "kegg_path:hsa05205", "kegg_path:hsa04010", "kegg_path:hsa04510", "kegg_path:hsa05132", "kegg_path:hsa05205", "R-HSA-109582", "R-HSA-114608", "R-HSA-1169410", "R-HSA-1280215", "R-HSA-1500931", "R-HSA-162582", "R-HSA-168256", "R-HSA-194315", "R-HSA-195258", "R-HSA-430116", "R-HSA-446353", "R-HSA-446728", "R-HSA-5627123", "R-HSA-76002", "R-HSA-76005", "R-HSA-8983711", "R-HSA-913531", "kegg_path:hsa04010", "kegg_path:hsa04510", "kegg_path:hsa05132", "kegg_path:hsa05205", "kegg_path:hsa04010", "kegg_path:hsa04510", "kegg_path:hsa05132", "kegg_path:hsa05205" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "P21333", "ensembl_id": "None", "entrez_id": "ENSG00000196924", "chromosome_number": "X" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "767" }, { "type": "SmallVariant", "id": "1298" }, { "type": "SmallVariant", "id": "3177" }, { "type": "SmallVariant", "id": "3241" }, { "type": "SmallVariant", "id": "3277" }, { "type": "SmallVariant", "id": "3314" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLNA/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLNA/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "240" }, { "type": "GeneCombination", "id": "410" }, { "type": "GeneCombination", "id": "1061" }, { "type": "GeneCombination", "id": "1086" }, { "type": "GeneCombination", "id": "1102" }, { "type": "GeneCombination", "id": "1114" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLNA/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLNA/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FLNA/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.390873", "status": "CU", "curator": null, "submitter": "cnachteg" } }