Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/SHH/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "273", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.880814" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI407" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/273/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/273/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DISP1" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/273/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/273/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/273/?format=api" } }, { "type": "GeneCombination", "id": "467", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:10.145533" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI678" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/467/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/467/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "FAT1" }, { "type": "Gene", "id": "NDST1" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/467/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/467/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/467/?format=api" } }, { "type": "GeneCombination", "id": "472", "attributes": { "gene_relationship": [ "Co-expression", "Directly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:10.363773" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI683" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/472/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/472/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "BOC" }, { "type": "Gene", "id": "SCUBE2" }, { "type": "Gene", "id": "SHH" }, { "type": "Gene", "id": "STK36" }, { "type": "Gene", "id": "WNT4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/472/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/472/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/472/?format=api" } }, { "type": "GeneCombination", "id": "475", "attributes": { "gene_relationship": [ "Same organelle", "Affecting the same tissue", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:10.491713" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI686" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/475/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/475/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CELSR1" }, { "type": "Gene", "id": "LRP2" }, { "type": "Gene", "id": "MKS1" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/475/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/475/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/475/?format=api" } }, { "type": "GeneCombination", "id": "486", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:10.942376" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI697" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/486/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/486/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DCHS1" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/486/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/486/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/486/?format=api" } }, { "type": "GeneCombination", "id": "1046", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.713438" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1486" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1046/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1046/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA2" }, { "type": "Gene", "id": "GLIS3" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1046/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1046/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1046/?format=api" } }, { "type": "GeneCombination", "id": "1047", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.717866" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1487" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1047/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1047/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1047/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1047/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1047/?format=api" } }, { "type": "GeneCombination", "id": "800", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.791762" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1085" }, { "type": "Combination", "id": "OLI1503" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/800/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/800/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "SHH" }, { "type": "Gene", "id": "TG" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/800/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/800/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/800/?format=api" } }, { "type": "GeneCombination", "id": "801", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.797976" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1086" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/801/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/801/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CDCA8" }, { "type": "Gene", "id": "SHH" }, { "type": "Gene", "id": "SLC26A4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/801/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/801/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/801/?format=api" } }, { "type": "GeneCombination", "id": "1082", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.084703" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1538" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1082/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1082/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "FGFR3" }, { "type": "Gene", "id": "FLRT3" }, { "type": "Gene", "id": "GHR" }, { "type": "Gene", "id": "LZTR1" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1082/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1082/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1082/?format=api" } }, { "type": "GeneCombination", "id": "1096", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Disease", "GPCR ligand binding", "Signal Transduction", "Signaling by GPCR" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.172433" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1552" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1096/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1096/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "LHCGR" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1096/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1096/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1096/?format=api" } }, { "type": "GeneCombination", "id": "1122", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Disease", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.405933" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1578" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1122/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1122/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "NRAS" }, { "type": "Gene", "id": "RXFP2" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1122/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1122/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1122/?format=api" } } ] }