Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/273/genes/?format=api
{ "data": [ { "type": "Gene", "id": "DISP1", "attributes": { "go_molecular_function": [ "peptide transmembrane transporter activity", "protein binding" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96F81", "ensembl_id": "ENSG00000154309", "entrez_id": "84976", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.911017" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "877" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DISP1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DISP1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "273" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DISP1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DISP1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DISP1/?format=api" } }, { "type": "Gene", "id": "SHH", "attributes": { "go_molecular_function": [ "['zinc ion binding', 'patched binding', 'laminin-1 binding', 'calcium ion binding', 'morphogen activity', 'endopeptidase activity', 'protein binding', 'glycosaminoglycan binding']" ], "pathway_id": [ "kegg_path:hsa04340", "kegg_path:hsa04360", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05217", "kegg_path:hsa05226", "R-HSA-162582", "R-HSA-1643685", "R-HSA-372790", "R-HSA-373080", "R-HSA-500792", "R-HSA-5358346", "R-HSA-5358351", "R-HSA-5362768", "R-HSA-5362798", "R-HSA-5387390", "R-HSA-5632681", "R-HSA-5632684", "R-HSA-5635838", "R-HSA-5658034", "R-HSA-5663202" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q15465", "ensembl_id": "None", "entrez_id": "ENSG00000164690", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.375806" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "876" }, { "type": "SmallVariant", "id": "1461" }, { "type": "SmallVariant", "id": "1475" }, { "type": "SmallVariant", "id": "1484" }, { "type": "SmallVariant", "id": "1514" }, { "type": "SmallVariant", "id": "2366" }, { "type": "SmallVariant", "id": "3130" }, { "type": "SmallVariant", "id": "3231" }, { "type": "SmallVariant", "id": "3262" }, { "type": "SmallVariant", "id": "3329" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SHH/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SHH/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 12 }, "data": [ { "type": "GeneCombination", "id": "273" }, { "type": "GeneCombination", "id": "467" }, { "type": "GeneCombination", "id": "472" }, { "type": "GeneCombination", "id": "475" }, { "type": "GeneCombination", "id": "486" }, { "type": "GeneCombination", "id": "1046" }, { "type": "GeneCombination", "id": "1047" }, { "type": "GeneCombination", "id": "800" }, { "type": "GeneCombination", "id": "801" }, { "type": "GeneCombination", "id": "1082" }, { "type": "GeneCombination", "id": "1096" }, { "type": "GeneCombination", "id": "1122" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SHH/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SHH/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SHH/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }