Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/NR5A1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "268", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.638397" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI401" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/268/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/268/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "SRD5A2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/268/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/268/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/268/?format=api" } }, { "type": "GeneCombination", "id": "267", "attributes": { "gene_relationship": [ "Indirectly interacting", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Monogenic experiments only", "Same pathway", "Similar function" ], "protein_interactions": [], "common_pathways": [ "Transcriptional regulation of testis differentiation", "Developmental Biology" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.607532" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI400" }, { "type": "Combination", "id": "OLI669" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/267/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/267/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "ZFPM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/267/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/267/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/267/?format=api" } }, { "type": "GeneCombination", "id": "384", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Metabolism of proteins" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:05.563529" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI572" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/384/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/384/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "INHA" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/384/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/384/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/384/?format=api" } }, { "type": "GeneCombination", "id": "385", "attributes": { "gene_relationship": [ "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signaling by Nuclear Receptors", "Ovarian steroidogenesis", "Nuclear Receptor transcription pathway", "Generic Transcription Pathway", "Disease", "Metabolism of lipids", "Gene expression (Transcription)", "GPCR downstream signalling", "RNA Polymerase II Transcription", "Metabolism", "Developmental Biology", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:05.648764" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI573" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/385/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "DOCK8" }, { "type": "Gene", "id": "FSHR" }, { "type": "Gene", "id": "NCOR1" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "POR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/385/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/?format=api" } }, { "type": "GeneCombination", "id": "386", "attributes": { "gene_relationship": [ "Directly interacting", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:05.751434" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI574" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/386/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/386/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "CACNG4" }, { "type": "Gene", "id": "FBLN2" }, { "type": "Gene", "id": "NAV1" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "SMAD6" }, { "type": "Gene", "id": "SRA1" }, { "type": "Gene", "id": "ZDHHC11" }, { "type": "Gene", "id": "ZFPM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/386/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/386/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/386/?format=api" } }, { "type": "GeneCombination", "id": "387", "attributes": { "gene_relationship": [ "Directly interacting", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:05.841376" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI575" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/387/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/387/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "DENND1A" }, { "type": "Gene", "id": "GDNF" }, { "type": "Gene", "id": "GLI2" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "SOX30" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/387/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/387/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/387/?format=api" } }, { "type": "GeneCombination", "id": "459", "attributes": { "gene_relationship": [ "Indirectly interacting", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Cushing syndrome", "Cortisol synthesis and secretion", "Cortisol synthesis and secretion" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:09.820790" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI667" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/459/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/459/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "STAR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/459/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/459/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/459/?format=api" } }, { "type": "GeneCombination", "id": "460", "attributes": { "gene_relationship": [ "Indirectly interacting", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Transcriptional regulation of testis differentiation" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:09.846844" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI668" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/460/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/460/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AMH" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/460/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/460/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/460/?format=api" } }, { "type": "GeneCombination", "id": "554", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:16.050025" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI766" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/554/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/554/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MAP3K1" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/554/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/554/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/554/?format=api" } }, { "type": "GeneCombination", "id": "738", "attributes": { "gene_relationship": [ "Directly interacting" ], "protein_interactions": [ "(AR, NR5A1)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:02.490973" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI998" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/738/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/738/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "AR" }, { "type": "Gene", "id": "MYH6" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/738/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/738/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/738/?format=api" } }, { "type": "GeneCombination", "id": "766", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2022-08-04T14:15:03.477020" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1046" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/766/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/766/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ADAMTS5" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "RAD50" }, { "type": "Gene", "id": "SYNE1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/766/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/766/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/766/?format=api" } }, { "type": "GeneCombination", "id": "763", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:53:46.325265" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1043" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/763/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/763/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "FIGLA" }, { "type": "Gene", "id": "NCOR2" }, { "type": "Gene", "id": "NOBOX" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/763/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/763/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/763/?format=api" } }, { "type": "GeneCombination", "id": "1055", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.852423" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1510" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1055/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1055/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CTU2" }, { "type": "Gene", "id": "MAP3K1" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1055/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1055/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1055/?format=api" } }, { "type": "GeneCombination", "id": "1094", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Developmental Biology" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:28.163977" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1550" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1094/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1094/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FLRT3" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1094/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1094/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1094/?format=api" } }, { "type": "GeneCombination", "id": "1101", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.205018" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1557" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1101/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1101/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "HSD17B6" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "PROK2" }, { "type": "Gene", "id": "SEMA3F" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1101/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1101/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1101/?format=api" } }, { "type": "GeneCombination", "id": "1102", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.248009" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1558" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1102/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1102/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "FGFR3" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "GLI2" }, { "type": "Gene", "id": "GPRC6A" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1102/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1102/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1102/?format=api" } }, { "type": "GeneCombination", "id": "1144", "attributes": { "gene_relationship": [ "Affecting the same tissue", "Monogenic experiments only", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:36:33.528420" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1617" }, { "type": "Combination", "id": "OLI1618" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1144/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1144/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DHX37" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1144/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1144/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1144/?format=api" } }, { "type": "GeneCombination", "id": "1235", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Post-translational protein modification", "SUMOylation", "Metabolism of proteins", "SUMO E3 ligases SUMOylate target proteins" ], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:23.101859" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1727" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1235/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1235/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FOXL2" }, { "type": "Gene", "id": "NR5A1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1235/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1235/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1235/?format=api" } } ] }