Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/MYO7A/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "75", "attributes": { "gene_relationship": [ "Indirectly interacting", "Directly interacting", "Same protein complex", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway", "Co-expression" ], "protein_interactions": [ "(CDH23, MYO7A)" ], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.570761" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI100" }, { "type": "Combination", "id": "OLI261" }, { "type": "Combination", "id": "OLI262" }, { "type": "Combination", "id": "OLI1033" }, { "type": "Combination", "id": "OLI1036" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/75/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/75/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "MYO7A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/75/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/75/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/75/?format=api" } }, { "type": "GeneCombination", "id": "76", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:48.605696" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI101" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/76/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/76/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ADGRV1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "USH2A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/76/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/76/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/76/?format=api" } }, { "type": "GeneCombination", "id": "77", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:48.638562" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI102" }, { "type": "Combination", "id": "OLI1034" }, { "type": "Combination", "id": "OLI1035" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/77/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/77/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ADGRV1" }, { "type": "Gene", "id": "MYO7A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/77/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/77/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/77/?format=api" } }, { "type": "GeneCombination", "id": "78", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:48.673165" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI103" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/78/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/78/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "USH1G" }, { "type": "Gene", "id": "USH2A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/78/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/78/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/78/?format=api" } }, { "type": "GeneCombination", "id": "80", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:48.740985" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI105" }, { "type": "Combination", "id": "OLI106" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/80/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/80/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "USH2A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/80/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/80/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/80/?format=api" } }, { "type": "GeneCombination", "id": "236", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Gene expression (Transcription)", "Basal cell carcinoma", "RNA Polymerase II Transcription", "Pathways in cancer", "Generic Transcription Pathway", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.363663" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI348" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/236/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "WNT9A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/236/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/?format=api" } }, { "type": "GeneCombination", "id": "240", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(CDH23, MYO7A)", "(MAML2, NOTCH2)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.806836" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI352" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/240/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/240/combinations/?format=api" } }, "genes": { "meta": { "count": 10 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "EVC" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "MAML2" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "NOTCH2" }, { "type": "Gene", "id": "PIK3R3" }, { "type": "Gene", "id": "PTPN11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/240/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/240/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/240/?format=api" } }, { "type": "GeneCombination", "id": "168", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Colocalization", "Same pathway", "Co-expression" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:53.530216" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI259" }, { "type": "Combination", "id": "OLI1038" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/168/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/168/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "PCDH15" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/168/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/168/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/168/?format=api" } }, { "type": "GeneCombination", "id": "238", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(CDH23, MYO7A)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.543112" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI350" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/238/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/238/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "FREM2" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/238/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/238/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/238/?format=api" } }, { "type": "GeneCombination", "id": "231", "attributes": { "gene_relationship": [ "Directly interacting", "Indirectly interacting", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(CDH23, MYO7A)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.016709" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI343" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/231/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/231/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "MAML1" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "RET" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/231/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/231/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/231/?format=api" } }, { "type": "GeneCombination", "id": "233", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.135012" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI345" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/233/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/233/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/233/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/233/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/233/?format=api" } }, { "type": "GeneCombination", "id": "412", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MAML2, NOTCH1)", "(MAML3, NOTCH1)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.602611" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI604" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/412/combinations/?format=api" } }, "genes": { "meta": { "count": 14 }, "data": [ { "type": "Gene", "id": "CUL4B" }, { "type": "Gene", "id": "DAPK1" }, { "type": "Gene", "id": "EMX2" }, { "type": "Gene", "id": "FREM2" }, { "type": "Gene", "id": "IGFBP2" }, { "type": "Gene", "id": "MAML2" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "NOTCH1" }, { "type": "Gene", "id": "PIK3R3" }, { "type": "Gene", "id": "TGFBI" }, { "type": "Gene", "id": "WNT9A" }, { "type": "Gene", "id": "WNT9B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/412/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/?format=api" } }, { "type": "GeneCombination", "id": "758", "attributes": { "gene_relationship": [ "Directly interacting", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [ "(MYO7A, USH1C)" ], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:54:20.569539" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1037" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/758/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/758/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "USH1C" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/758/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/758/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/758/?format=api" } }, { "type": "GeneCombination", "id": "757", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:54:33.335091" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1032" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/757/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/757/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "SHROOM2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/757/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/757/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/757/?format=api" } }, { "type": "GeneCombination", "id": "1256", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:23.513175" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1749" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1256/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1256/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "SOX8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1256/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1256/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1256/?format=api" } }, { "type": "GeneCombination", "id": "1253", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:29:35.180484" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1746" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1253/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1253/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "GLI2" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "VDR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1253/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1253/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1253/?format=api" } } ] }