Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/genecombinations/75/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI100", "attributes": { "scores": { "familial_evidence": 1, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 0, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 1 }, "omim_id": [ "OMIM276900", "OMIM606943", "OMIM276904", "OMIM601067", "OMIM612632", "OMIM602083", "OMIM614990", "OMIM618632", "OMIM614869", "OMIM602097" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2021-11-18T16:33:41.879433" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "231169" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI100/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI100/diseases/?format=api" } }, "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "207" }, { "type": "SmallVariant", "id": "208" }, { "type": "SmallVariant", "id": "1975" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI100/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI100/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "618" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI100/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI100/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI100/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI100/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "75" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI100/?format=api" } }, { "type": "Combination", "id": "OLI261", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM276900", "OMIM606943", "OMIM276904", "OMIM601067", "OMIM612632", "OMIM602083", "OMIM614990", "OMIM618632", "OMIM614869", "OMIM602097" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:41.774574" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "231169" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI261/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI261/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "507" }, { "type": "SmallVariant", "id": "508" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI261/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI261/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "681" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI261/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI261/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI261/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI261/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "75" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI261/?format=api" } }, { "type": "Combination", "id": "OLI262", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 2, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM276900", "OMIM606943", "OMIM276904", "OMIM601067", "OMIM612632", "OMIM602083", "OMIM614990", "OMIM618632", "OMIM614869", "OMIM602097" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "East Asian", "lastmodified": "2021-11-16T17:59:41.789652" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "231169" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI262/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI262/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "509" }, { "type": "SmallVariant", "id": "510" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI262/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI262/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "681" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI262/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI262/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI262/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI262/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "75" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI262/?format=api" } }, { "type": "Combination", "id": "OLI1033", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 0, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 1, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM612925", "OMIM609814", "OMIM612922", "OMIM235400", "OMIM615008", "OMIM156000", "OMIM612923", "OMIM612924", "OMIM612926" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-10-25T15:06:30.744281" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "2134" }, { "type": "Disease", "id": "-19" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1033/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1033/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2234" }, { "type": "SmallVariant", "id": "2235" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1033/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1033/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "905" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1033/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1033/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1033/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1033/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "75" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1033/?format=api" } }, { "type": "Combination", "id": "OLI1036", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 2, "statistical_evidence_knowledge": 1, "statistical_evidence_metascore": 2, "functional_gene_evidence_manual": 3, "functional_gene_evidence_manual_harmonized": 3, "functional_gene_evidence_knowledge": 2, "functional_gene_evidence_metascore": 3, "functional_variant_evidence_manual": 1, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 2, "functional_final_metascore": 2, "final_manual": 2, "final_metascore": 2 }, "omim_id": [ "OMIM612925", "OMIM609814", "OMIM612922", "OMIM235400", "OMIM615008", "OMIM156000", "OMIM612923", "OMIM612924", "OMIM612926" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "European/Caucasian", "lastmodified": "2023-10-25T15:06:30.753011" }, "relationships": { "diseases": { "meta": { "count": 2 }, "data": [ { "type": "Disease", "id": "2134" }, { "type": "Disease", "id": "-19" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1036/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1036/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2240" }, { "type": "SmallVariant", "id": "2241" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1036/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1036/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "905" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1036/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1036/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1036/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1036/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "75" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1036/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 5 } }