Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/FGFR1/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "1973", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": null, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "8", "annotation_flag": "not_found_in_databases", "lastmodified": "2021-10-18T11:01:22.351932", "ref_allele": null, "alt_allele": null, "cdna_change": "r.spl_site3", "protein_change": null, "transcript_id": "NM_015850.3", "dbsnp_id": "NA", "variant_effect": "splicing" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI915" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1973/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1973/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1973/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1973/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1973/?format=api" } }, { "type": "SmallVariant", "id": "2820", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "-", "pp2_hvar_prediction": "-", "cadd_prediction": null, "mutationtaster_prediction": "-" }, "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "8", "annotation_flag": null, "lastmodified": "2023-05-16T12:02:48.898192", "ref_allele": null, "alt_allele": null, "cdna_change": "c.340-344delTTCTC", "protein_change": "p.Phe114fs13", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1336" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2820/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2820/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2820/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2820/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2820/?format=api" } }, { "type": "SmallVariant", "id": "37", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.701467, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38285504, "genomic_position_hg38": 38427986, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:40.738120", "ref_allele": "G", "alt_allele": "C", "cdna_change": "c.556C>G", "protein_change": "p.Pro186Ala", "transcript_id": "NM_023110.2", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI019" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/37/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/37/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/37/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/37/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/37/?format=api" } }, { "type": "SmallVariant", "id": "77", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 4.141403, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38287386, "genomic_position_hg38": 38429868, "chromosome": "8", "annotation_flag": "manually_attributed", "lastmodified": "2023-06-06T16:57:40.980619", "ref_allele": "GCAGCCGA", "alt_allele": "G", "cdna_change": "c.165_171del", "protein_change": "p.Arg56GlyfsTer45", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI036" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/77/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/77/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/77/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/77/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/77/?format=api" } }, { "type": "SmallVariant", "id": "147", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.923684, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38282215, "genomic_position_hg38": 38424697, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:41.389825", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.748C>T", "protein_change": "p.Arg250Trp", "transcript_id": "NM_023110.2", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI075" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/147/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/147/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/147/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/147/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/147/?format=api" } }, { "type": "SmallVariant", "id": "379", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 6.144e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0003682, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 7.605e-05, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.912501, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38287208, "genomic_position_hg38": 38429690, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.742644", "ref_allele": "T", "alt_allele": "C", "cdna_change": "c.350A>G", "protein_change": "p.Asn117Ser", "transcript_id": "NM_023110.2", "dbsnp_id": "rs780765366", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI195" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/379/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/379/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/379/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/379/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/379/?format=api" } }, { "type": "SmallVariant", "id": "382", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.702588, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38283669, "genomic_position_hg38": 38426151, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.761649", "ref_allele": "A", "alt_allele": "G", "cdna_change": "c.716T>C", "protein_change": "p.Ile239Thr", "transcript_id": "NM_023110.2", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI196" }, { "type": "Combination", "id": "OLI373" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/382/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/382/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/382/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/382/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/382/?format=api" } }, { "type": "SmallVariant", "id": "384", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Benign", "cadd_prediction": 4.873538, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38282214, "genomic_position_hg38": 38424696, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.774151", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.749G>A", "protein_change": "p.Arg250Gln", "transcript_id": "NM_023110.2", "dbsnp_id": "rs121909645", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI197" }, { "type": "Combination", "id": "OLI367" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/384/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/384/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/384/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/384/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/384/?format=api" } }, { "type": "SmallVariant", "id": "386", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 7.792479, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38273388, "genomic_position_hg38": 38415870, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.786429", "ref_allele": "C", "alt_allele": "G", "cdna_change": null, "protein_change": "p.Lys618Asn", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI198" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/386/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/386/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/386/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/386/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/386/?format=api" } }, { "type": "SmallVariant", "id": "388", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0008, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 1.202e-05, "gnomad_AFR_maf": 0.0001291, "gnomad_AMR_maf": 2.896e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.927332, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 38275767, "genomic_position_hg38": 38418249, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.799033", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.1409G>T", "protein_change": "p.Arg470Leu", "transcript_id": "NM_023110.2", "dbsnp_id": "rs121909637", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI199" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/388/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/388/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/388/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/388/gene/?format=api" }, "data": { "type": "Gene", "id": "FGFR1" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/388/?format=api" } }, { "type": "SmallVariant", "id": "398", "attributes": { "frequencies": { "KGP_genomes_maf": null, 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