Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/63/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BBS12", "attributes": { "go_molecular_function": [ "['ATP binding', 'protein binding', 'ATP hydrolysis activity']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q6ZW61", "ensembl_id": "None", "entrez_id": "ENSG00000181004", "chromosome_number": "4", "lastmodified": "2021-10-18T11:00:44.962621" }, "relationships": { "variant_set": { "meta": { "count": 24 }, "data": [ { "type": "SmallVariant", "id": "344" }, { "type": "SmallVariant", "id": "155" }, { "type": "SmallVariant", "id": "156" }, { "type": "SmallVariant", "id": "160" }, { "type": "SmallVariant", "id": "161" }, { "type": "SmallVariant", "id": "162" }, { "type": "SmallVariant", "id": "164" }, { "type": "SmallVariant", "id": "174" }, { "type": "SmallVariant", "id": "176" }, { "type": "SmallVariant", "id": "177" }, { "type": "SmallVariant", "id": "298" }, { "type": "SmallVariant", "id": "299" }, { "type": "SmallVariant", "id": "346" }, { "type": "SmallVariant", "id": "625" }, { "type": "SmallVariant", "id": "627" }, { "type": "SmallVariant", "id": "2418" }, { "type": "SmallVariant", "id": "2431" }, { "type": "SmallVariant", "id": "2432" }, { "type": "SmallVariant", "id": "2433" }, { "type": "SmallVariant", "id": "2435" }, { "type": "SmallVariant", "id": "2436" }, { "type": "SmallVariant", "id": "3050" }, { "type": "SmallVariant", "id": "3052" }, { "type": "SmallVariant", "id": "3054" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS12/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS12/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "56" }, { "type": "GeneCombination", "id": "57" }, { "type": "GeneCombination", "id": "58" }, { "type": "GeneCombination", "id": "59" }, { "type": "GeneCombination", "id": "62" }, { "type": "GeneCombination", "id": "63" }, { "type": "GeneCombination", "id": "121" }, { "type": "GeneCombination", "id": "212" }, { "type": "GeneCombination", "id": "1023" }, { "type": "GeneCombination", "id": "1024" }, { "type": "GeneCombination", "id": "1022" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS12/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS12/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS12/?format=api" } }, { "type": "Gene", "id": "BBS9", "attributes": { "go_molecular_function": [ "['molecular_function', 'protein binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q3SYG4", "ensembl_id": "None", "entrez_id": "ENSG00000122507", "chromosome_number": "7", "lastmodified": "2021-10-18T11:00:44.727463" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "179" }, { "type": "SmallVariant", "id": "180" }, { "type": "SmallVariant", "id": "290" }, { "type": "SmallVariant", "id": "896" }, { "type": "SmallVariant", "id": "2422" }, { "type": "SmallVariant", "id": "2438" }, { "type": "SmallVariant", "id": "2440" }, { "type": "SmallVariant", "id": "3046" }, { "type": "SmallVariant", "id": "3047" }, { "type": "SmallVariant", "id": "3048" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS9/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS9/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "63" }, { "type": "GeneCombination", "id": "105" }, { "type": "GeneCombination", "id": "278" }, { "type": "GeneCombination", "id": "421" }, { "type": "GeneCombination", "id": "821" }, { "type": "GeneCombination", "id": "1021" }, { "type": "GeneCombination", "id": "1020" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS9/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS9/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS9/?format=api" } }, { "type": "Gene", "id": "MKKS", "attributes": { "go_molecular_function": [ "['unfolded protein binding', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding', 'ATP hydrolysis activity', 'ATP binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NPJ1", "ensembl_id": "None", "entrez_id": "ENSG00000125863", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.476702" }, "relationships": { "variant_set": { "meta": { "count": 15 }, "data": [ { "type": "SmallVariant", "id": "125" }, { "type": "SmallVariant", "id": "130" }, { "type": "SmallVariant", "id": "133" }, { "type": "SmallVariant", "id": "172" }, { "type": "SmallVariant", "id": "178" }, { "type": "SmallVariant", "id": "293" }, { "type": "SmallVariant", "id": "348" }, { "type": "SmallVariant", "id": "435" }, { "type": "SmallVariant", "id": "437" }, { "type": "SmallVariant", "id": "2437" }, { "type": "SmallVariant", "id": "3039" }, { "type": "SmallVariant", "id": "3040" }, { "type": "SmallVariant", "id": "3042" }, { "type": "SmallVariant", "id": "3484" }, { "type": "SmallVariant", "id": "3493" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MKKS/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MKKS/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "47" }, { "type": "GeneCombination", "id": "61" }, { "type": "GeneCombination", "id": "63" }, { "type": "GeneCombination", "id": "420" }, { "type": "GeneCombination", "id": "45" }, { "type": "GeneCombination", "id": "1018" }, { "type": "GeneCombination", "id": "1019" }, { "type": "GeneCombination", "id": "1017" }, { "type": "GeneCombination", "id": "1172" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MKKS/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MKKS/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MKKS/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }