Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/BBS12/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "56", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway", "Similar function" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:47.732396" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI078" }, { "type": "Combination", "id": "OLI142" }, { "type": "Combination", "id": "OLI1128" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/56/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/56/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/56/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/56/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/56/?format=api" } }, { "type": "GeneCombination", "id": "57", "attributes": { "gene_relationship": [ "Involved in the same disease", "Similar function", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.779901" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI079" }, { "type": "Combination", "id": "OLI1127" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/57/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/57/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/?format=api" } }, { "type": "GeneCombination", "id": "58", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.823830" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI147" }, { "type": "Combination", "id": "OLI080" }, { "type": "Combination", "id": "OLI323" }, { "type": "Combination", "id": "OLI1120" }, { "type": "Combination", "id": "OLI1129" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/58/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/58/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/58/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/58/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/58/?format=api" } }, { "type": "GeneCombination", "id": "59", "attributes": { "gene_relationship": [ "Involved in the same disease", "Similar function", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS12, BBS4)", "(BBS2, BBS4)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.861759" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI081" }, { "type": "Combination", "id": "OLI082" }, { "type": "Combination", "id": "OLI1121" }, { "type": "Combination", "id": "OLI1132" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/59/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/59/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "BBS2" }, { "type": "Gene", "id": "BBS4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/59/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/59/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/59/?format=api" } }, { "type": "GeneCombination", "id": "62", "attributes": { "gene_relationship": [ "Involved in the same disease", "Directly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS12, BBS4)" ], "common_pathways": [ "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.024964" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI086" }, { "type": "Combination", "id": "OLI1130" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/62/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/62/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "BBS4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/62/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/62/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/62/?format=api" } }, { "type": "GeneCombination", "id": "63", "attributes": { "gene_relationship": [ "Involved in the same disease", "Similar function", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS12, MKKS)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.091017" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI087" }, { "type": "Combination", "id": "OLI1131" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/63/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/63/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "BBS9" }, { "type": "Gene", "id": "MKKS" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/63/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/63/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/63/?format=api" } }, { "type": "GeneCombination", "id": "121", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:50.872004" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI173" }, { "type": "Combination", "id": "OLI174" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/121/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/121/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "BBS2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/121/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/121/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/121/?format=api" } }, { "type": "GeneCombination", "id": "212", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:55.482978" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI322" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/212/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/212/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "BBS2" }, { "type": "Gene", "id": "INPP5E" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/212/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/212/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/212/?format=api" } }, { "type": "GeneCombination", "id": "1023", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.559636" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1454" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1023/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1023/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "TRIM32" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1023/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1023/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1023/?format=api" } }, { "type": "GeneCombination", "id": "1024", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.563890" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1455" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1024/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1024/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "SDCCAG8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1024/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1024/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1024/?format=api" } }, { "type": "GeneCombination", "id": "1022", "attributes": { "gene_relationship": [ "Colocalization", "Indirectly interacting", "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:25:56.135793" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1453" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1022/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1022/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS12" }, { "type": "Gene", "id": "PDE6B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1022/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1022/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1022/?format=api" } } ] }