Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/WDR11/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "10", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:45.660586" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI014" }, { "type": "Combination", "id": "OLI1164" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/10/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/10/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/10/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/10/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/10/?format=api" } }, { "type": "GeneCombination", "id": "245", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:58.089193" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI357" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/245/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/245/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "HS6ST1" }, { "type": "Gene", "id": "IL17RD" }, { "type": "Gene", "id": "LEPR" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/245/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/245/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/245/?format=api" } }, { "type": "GeneCombination", "id": "410", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(CYP1A1, PTPN11)", "(FLNA, NRP1)", "(MAML1, MAML3)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.207559" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI602" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/410/combinations/?format=api" } }, "genes": { "meta": { "count": 17 }, "data": [ { "type": "Gene", "id": "BNC2" }, { "type": "Gene", "id": "NRP1" }, { "type": "Gene", "id": "PROP1" }, { "type": "Gene", "id": "PTPN11" }, { "type": "Gene", "id": "MAML1" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "IRX5" }, { "type": "Gene", "id": "ATF3" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "IRX6" }, { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "HOXA13" }, { "type": "Gene", "id": "WDR11" }, { "type": "Gene", "id": "EYA1" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "MAMLD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/410/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/?format=api" } }, { "type": "GeneCombination", "id": "411", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MAML3, NOTCH2)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.345230" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI603" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/411/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/411/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "EVC" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "NOTCH2" }, { "type": "Gene", "id": "PPARGC1B" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/411/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/411/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/411/?format=api" } }, { "type": "GeneCombination", "id": "621", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.194198" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI854" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/621/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/621/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "RELN" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/621/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/621/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/621/?format=api" } }, { "type": "GeneCombination", "id": "851", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2022-08-04T14:15:06.373659" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1168" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/851/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/851/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRH1" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/851/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/851/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/851/?format=api" } }, { "type": "GeneCombination", "id": "820", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.134983" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1115" }, { "type": "Combination", "id": "OLI1357" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/820/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/820/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SEMA3A" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/820/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/820/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/820/?format=api" } }, { "type": "GeneCombination", "id": "886", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.690865" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1263" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/886/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/886/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SEMA3E" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/886/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/886/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/886/?format=api" } }, { "type": "GeneCombination", "id": "892", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.726119" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1270" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/892/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/892/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/892/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/892/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/892/?format=api" } }, { "type": "GeneCombination", "id": "908", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.830592" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1299" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/908/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/908/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FEZF1" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/908/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/908/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/908/?format=api" } }, { "type": "GeneCombination", "id": "976", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.305188" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1399" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/976/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/976/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/976/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/976/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/976/?format=api" } }, { "type": "GeneCombination", "id": "848", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:28.458422" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1165" }, { "type": "Combination", "id": "OLI1595" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/848/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/848/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/848/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/848/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/848/?format=api" } } ] }