Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/TARDBP/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "183", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.156353" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI279" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/183/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/183/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "TARDBP" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/183/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/183/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/183/?format=api" } }, { "type": "GeneCombination", "id": "271", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(SQSTM1, TARDBP)" ], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.785959" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI404" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/271/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/271/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SQSTM1" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/271/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/271/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/271/?format=api" } }, { "type": "GeneCombination", "id": "295", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Membrane Trafficking", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:01.009925" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI437" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/295/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/295/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "OPTN" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/295/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/295/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/295/?format=api" } }, { "type": "GeneCombination", "id": "452", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:09.589012" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI659" }, { "type": "Combination", "id": "OLI1702" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/452/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/452/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SETX" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/452/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/452/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/452/?format=api" } }, { "type": "GeneCombination", "id": "916", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.890245" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1309" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/916/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/916/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GBA" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/916/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/916/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/916/?format=api" } }, { "type": "GeneCombination", "id": "917", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [ "(GBA, PRKN)", "(PRKN, TARDBP)" ], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.896576" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1310" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/917/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/917/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "GBA" }, { "type": "Gene", "id": "PRKN" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/917/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/917/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/917/?format=api" } }, { "type": "GeneCombination", "id": "919", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [ "(LRRK2, PRKN)", "(PRKN, TARDBP)" ], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.907416" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1312" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/919/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/919/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "LRRK2" }, { "type": "Gene", "id": "PRKN" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/919/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/919/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/919/?format=api" } }, { "type": "GeneCombination", "id": "553", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.576674" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI765" }, { "type": "Combination", "id": "OLI770" }, { "type": "Combination", "id": "OLI1458" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/553/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/553/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "C9orf72" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/553/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/553/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/553/?format=api" } }, { "type": "GeneCombination", "id": "1027", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.580912" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1459" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1027/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1027/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SPG11" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1027/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1027/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1027/?format=api" } }, { "type": "GeneCombination", "id": "1128", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:28.440950" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1588" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1128/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1128/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "NEK1" }, { "type": "Gene", "id": "TARDBP" }, { "type": "Gene", "id": "VEGFA" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1128/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1128/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1128/?format=api" } }, { "type": "GeneCombination", "id": "1146", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:21.281143" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1620" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1146/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1146/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ARHGEF28" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1146/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1146/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1146/?format=api" } }, { "type": "GeneCombination", "id": "1155", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MATR3, TARDBP)" ], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.464790" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1636" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1155/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1155/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MATR3" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1155/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1155/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1155/?format=api" } }, { "type": "GeneCombination", "id": "1157", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.499557" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1638" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1157/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1157/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DCTN1" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1157/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1157/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1157/?format=api" } } ] }