Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/NOTCH1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "405", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:06.720619" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI597" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/405/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/405/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "EVC" }, { "type": "Gene", "id": "GRID1" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "NOTCH1" }, { "type": "Gene", "id": "RET" }, { "type": "Gene", "id": "RIPK4" }, { "type": "Gene", "id": "ZBTB16" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/405/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/405/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/405/?format=api" } }, { "type": "GeneCombination", "id": "408", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MAML1, NOTCH1)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:06.870457" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI600" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/408/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/408/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "COL9A3" }, { "type": "Gene", "id": "MAML1" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "NOTCH1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/408/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/408/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/408/?format=api" } }, { "type": "GeneCombination", "id": "412", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MAML2, NOTCH1)", "(MAML3, NOTCH1)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.602611" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI604" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/412/combinations/?format=api" } }, "genes": { "meta": { "count": 14 }, "data": [ { "type": "Gene", "id": "CUL4B" }, { "type": "Gene", "id": "DAPK1" }, { "type": "Gene", "id": "EMX2" }, { "type": "Gene", "id": "FREM2" }, { "type": "Gene", "id": "IGFBP2" }, { "type": "Gene", "id": "MAML2" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "NOTCH1" }, { "type": "Gene", "id": "PIK3R3" }, { "type": "Gene", "id": "TGFBI" }, { "type": "Gene", "id": "WNT9A" }, { "type": "Gene", "id": "WNT9B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/412/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/412/?format=api" } }, { "type": "GeneCombination", "id": "612", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:18.762416" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI843" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/612/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/612/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NOTCH1" }, { "type": "Gene", "id": "SLIT2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/612/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/612/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/612/?format=api" } } ] }