Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/CYP1A1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "236", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Gene expression (Transcription)", "Basal cell carcinoma", "RNA Polymerase II Transcription", "Pathways in cancer", "Generic Transcription Pathway", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.363663" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI348" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/236/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "MYO7A" }, { "type": "Gene", "id": "WNT9A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/236/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/236/?format=api" } }, { "type": "GeneCombination", "id": "237", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Disease", "Metabolism of lipids", "Diseases of signal transduction by growth factor receptors and second messengers", "Metabolism", "Developmental Biology", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:57.432585" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI349" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/237/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/237/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "PIK3R3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/237/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/237/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/237/?format=api" } }, { "type": "GeneCombination", "id": "405", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:06.720619" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI597" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/405/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/405/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "EVC" }, { "type": "Gene", "id": "GRID1" }, { "type": "Gene", "id": "MAMLD1" }, { "type": "Gene", "id": "NOTCH1" }, { "type": "Gene", "id": "RET" }, { "type": "Gene", "id": "RIPK4" }, { "type": "Gene", "id": "ZBTB16" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/405/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/405/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/405/?format=api" } }, { "type": "GeneCombination", "id": "410", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(CYP1A1, PTPN11)", "(FLNA, NRP1)", "(MAML1, MAML3)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:07.207559" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI602" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/410/combinations/?format=api" } }, "genes": { "meta": { "count": 17 }, "data": [ { "type": "Gene", "id": "BNC2" }, { "type": "Gene", "id": "NRP1" }, { "type": "Gene", "id": "PROP1" }, { "type": "Gene", "id": "PTPN11" }, { "type": "Gene", "id": "MAML1" }, { "type": "Gene", "id": "MAML3" }, { "type": "Gene", "id": "IRX5" }, { "type": "Gene", "id": "ATF3" }, { "type": "Gene", "id": "FRAS1" }, { "type": "Gene", "id": "IRX6" }, { "type": "Gene", "id": "CYP1A1" }, { "type": "Gene", "id": "HOXA13" }, { "type": "Gene", "id": "WDR11" }, { "type": "Gene", "id": "EYA1" }, { "type": "Gene", "id": "GLI3" }, { "type": "Gene", "id": "FLNA" }, { "type": "Gene", "id": "MAMLD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/410/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/410/?format=api" } } ] }