Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/237/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CYP1A1", "attributes": { "go_molecular_function": [ "oxygen binding", "lyase activity", "hydroperoxy icosatetraenoate dehydratase activity", "aromatase activity", "metal ion binding", "monooxygenase activity", "oxidoreductase activity" ], "pathway_id": [ "kegg_path:hsa04913", "kegg_path:hsa04913", "R-HSA-8978868", "R-HSA-2142670", "R-HSA-1430728", "R-HSA-2142816", "R-HSA-9018677", "kegg_path:hsa05204", "kegg_path:hsa05204", "R-HSA-1989781", "R-HSA-211859", "kegg_path:hsa00380", "kegg_path:hsa00380", "R-HSA-211897", "R-HSA-211945", "kegg_path:hsa00140", "kegg_path:hsa01100", "kegg_path:hsa00140", "kegg_path:hsa01100", "R-HSA-556833", "R-HSA-9018681", "kegg_path:hsa00830", "kegg_path:hsa00830", "R-HSA-211981", "R-HSA-2142753", "R-HSA-9018678", "kegg_path:hsa00980", "kegg_path:hsa00980", "R-HSA-400206" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P04798", "ensembl_id": "ENSG00000140465", "entrez_id": "1543", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.968652" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "738" }, { "type": "SmallVariant", "id": "743" }, { "type": "SmallVariant", "id": "1269" }, { "type": "SmallVariant", "id": "1296" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CYP1A1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CYP1A1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "236" }, { "type": "GeneCombination", "id": "237" }, { "type": "GeneCombination", "id": "405" }, { "type": "GeneCombination", "id": "410" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CYP1A1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CYP1A1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CYP1A1/?format=api" } }, { "type": "Gene", "id": "MAMLD1", "attributes": { "go_molecular_function": [ "['molecular_function']" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-157118", "R-HSA-162582", "R-HSA-1643685", "R-HSA-186712", "R-HSA-1912408", "R-HSA-1912422", "R-HSA-1980143", "R-HSA-1980145", "R-HSA-210744", "R-HSA-2122947", "R-HSA-212436", "R-HSA-2197563", "R-HSA-2644602", "R-HSA-2644603", "R-HSA-2644606", "R-HSA-2894858", "R-HSA-2894862", "R-HSA-350054", "R-HSA-5663202", "R-HSA-73857", "R-HSA-74160", "R-HSA-8878159", "R-HSA-8941856", "R-HSA-9012852", "R-HSA-9013508", "R-HSA-9013694", "R-HSA-9013695", "R-HSA-1266738", "R-HSA-157118", "R-HSA-162582", "R-HSA-1643685", "R-HSA-186712", "R-HSA-1912408", "R-HSA-1912422", "R-HSA-1980143", "R-HSA-1980145", "R-HSA-210744", "R-HSA-2122947", "R-HSA-212436", "R-HSA-2197563", "R-HSA-2644602", "R-HSA-2644603", "R-HSA-2644606", "R-HSA-2894858", "R-HSA-2894862", "R-HSA-350054", "R-HSA-5663202", "R-HSA-73857", "R-HSA-74160", "R-HSA-8878159", "R-HSA-8941856", "R-HSA-9012852", "R-HSA-9013508", "R-HSA-9013694", "R-HSA-9013695" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q13495", "ensembl_id": "None", "entrez_id": "ENSG00000013619", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.997839" }, "relationships": { "variant_set": { "meta": { "count": 22 }, "data": [ { "type": "SmallVariant", "id": "581" }, { "type": "SmallVariant", "id": "717" }, { "type": "SmallVariant", "id": "722" }, { "type": "SmallVariant", "id": "729" }, { "type": "SmallVariant", "id": "733" }, { "type": "SmallVariant", "id": "736" }, { "type": "SmallVariant", "id": "742" }, { "type": "SmallVariant", "id": "745" }, { "type": "SmallVariant", "id": "752" }, { "type": "SmallVariant", "id": "757" }, { "type": "SmallVariant", "id": "1268" }, { "type": "SmallVariant", "id": "1278" }, { "type": "SmallVariant", "id": "1280" }, { "type": "SmallVariant", "id": "1283" }, { "type": "SmallVariant", "id": "1294" }, { "type": "SmallVariant", "id": "1310" }, { "type": "SmallVariant", "id": "1316" }, { "type": "SmallVariant", "id": "3192" }, { "type": "SmallVariant", "id": "3200" }, { "type": "SmallVariant", "id": "3252" }, { "type": "SmallVariant", "id": "3259" }, { "type": "SmallVariant", "id": "3325" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAMLD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAMLD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 26 }, "data": [ { "type": "GeneCombination", "id": "236" }, { "type": "GeneCombination", "id": "240" }, { "type": "GeneCombination", "id": "200" }, { "type": "GeneCombination", "id": "237" }, { "type": "GeneCombination", "id": "238" }, { "type": "GeneCombination", "id": "231" }, { "type": "GeneCombination", "id": "232" }, { "type": "GeneCombination", "id": "233" }, { "type": "GeneCombination", "id": "234" }, { "type": "GeneCombination", "id": "235" }, { "type": "GeneCombination", "id": "239" }, { "type": "GeneCombination", "id": "406" }, { "type": "GeneCombination", "id": "407" }, { "type": "GeneCombination", "id": "408" }, { "type": "GeneCombination", "id": "405" }, { "type": "GeneCombination", "id": "409" }, { "type": "GeneCombination", "id": "410" }, { "type": "GeneCombination", "id": "411" }, { "type": "GeneCombination", "id": "412" }, { "type": "GeneCombination", "id": "1067" }, { "type": "GeneCombination", "id": "1068" }, { "type": "GeneCombination", "id": "1091" }, { "type": "GeneCombination", "id": "1092" }, { "type": "GeneCombination", "id": "1095" }, { "type": "GeneCombination", "id": "1120" }, { "type": "GeneCombination", "id": "1122" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAMLD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAMLD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MAMLD1/?format=api" } }, { "type": "Gene", "id": "PIK3R3", "attributes": { "go_molecular_function": [ "1-phosphatidylinositol-3-kinase regulator activity", "1-phosphatidylinositol-3-kinase activity", "protein binding" ], "pathway_id": [ "R-HSA-8853659", "R-HSA-5663202", "kegg_path:hsa04919", "kegg_path:hsa05200", "kegg_path:hsa04218", "kegg_path:hsa04933", "kegg_path:hsa05167", "kegg_path:hsa04015", "kegg_path:hsa05166", "R-HSA-1266738", "kegg_path:hsa04071", "kegg_path:hsa05131", "kegg_path:hsa04931", "kegg_path:hsa05211", "kegg_path:hsa05171", "kegg_path:hsa05169", "kegg_path:hsa04915", "kegg_path:hsa04923", "kegg_path:hsa05163", "kegg_path:hsa04150", "kegg_path:hsa05235", "kegg_path:hsa04973", "kegg_path:hsa05161", "R-HSA-199418", "kegg_path:hsa04012", "kegg_path:hsa05100", "kegg_path:hsa05220", "kegg_path:hsa01522", "R-HSA-9006934", "kegg_path:hsa01521", "kegg_path:hsa05206", "kegg_path:hsa01524", "kegg_path:hsa04750", "kegg_path:hsa04613", "kegg_path:hsa05226", "kegg_path:hsa04910", "kegg_path:hsa05017", "kegg_path:hsa05142", "kegg_path:hsa05020", "kegg_path:hsa04066", "R-HSA-422475", "kegg_path:hsa05170", "kegg_path:hsa04666", "R-HSA-9675108", "kegg_path:hsa05214", "kegg_path:hsa04072", "kegg_path:hsa04550", "kegg_path:hsa04370", "R-HSA-168256", "kegg_path:hsa04140", "kegg_path:hsa04211", "kegg_path:hsa05231", "R-HSA-1433557", "kegg_path:hsa04929", "R-HSA-388396", "R-HSA-8939211", "kegg_path:hsa05165", "kegg_path:hsa05168", "kegg_path:hsa05224", "R-HSA-1483255", "kegg_path:hsa04070", "kegg_path:hsa05010", "kegg_path:hsa05135", "kegg_path:hsa05213", "kegg_path:hsa05223", "kegg_path:hsa05164", "kegg_path:hsa04152", "kegg_path:hsa05205", "kegg_path:hsa04725", "kegg_path:hsa04917", "kegg_path:hsa04625", "kegg_path:hsa04660", "kegg_path:hsa04620", "R-HSA-416476", "kegg_path:hsa04024", "kegg_path:hsa04935", "kegg_path:hsa04930", "kegg_path:hsa05418", "kegg_path:hsa04151", "kegg_path:hsa04360", "kegg_path:hsa05212", "kegg_path:hsa04630", "kegg_path:hsa05160", "kegg_path:hsa04062", "kegg_path:hsa04932", "kegg_path:hsa04914", "kegg_path:hsa04960", "kegg_path:hsa04662", "R-HSA-1280215", "R-HSA-76002", "kegg_path:hsa04068", "kegg_path:hsa05225", "R-HSA-372790", "R-HSA-9006925", "kegg_path:hsa04810", "kegg_path:hsa04670", "kegg_path:hsa05210", "R-HSA-912526", "kegg_path:hsa04380", "kegg_path:hsa04510", "R-HSA-449147", "kegg_path:hsa04722", "kegg_path:hsa04611", "kegg_path:hsa05162", "kegg_path:hsa04668", "kegg_path:hsa05203", "R-HSA-114604", "kegg_path:hsa05146", "kegg_path:hsa05215", "kegg_path:hsa04664", "kegg_path:hsa04650", "kegg_path:hsa05221", "kegg_path:hsa05230", "kegg_path:hsa04926", "R-HSA-389356", "kegg_path:hsa05222", "kegg_path:hsa05218", "kegg_path:hsa04210", "kegg_path:hsa04213", "kegg_path:hsa04014", "kegg_path:hsa05169", "kegg_path:hsa04915", "R-HSA-162582", "kegg_path:hsa05171", "kegg_path:hsa04931", "kegg_path:hsa05211", "kegg_path:hsa04071", "kegg_path:hsa05131", "kegg_path:hsa01522", "kegg_path:hsa04012", "kegg_path:hsa05100", "kegg_path:hsa05220", "kegg_path:hsa05161", "kegg_path:hsa04973", "kegg_path:hsa04923", "kegg_path:hsa04150", "kegg_path:hsa05235", "kegg_path:hsa05163", "kegg_path:hsa04919", "kegg_path:hsa05200", "R-HSA-388841", "R-HSA-912631", "R-HSA-1483257", "R-HSA-2219530", "kegg_path:hsa05166", "R-HSA-109582", "kegg_path:hsa04015", "kegg_path:hsa04933", "kegg_path:hsa05167", "kegg_path:hsa04218", "kegg_path:hsa04929", "kegg_path:hsa04211", "kegg_path:hsa05231", "kegg_path:hsa04140", "R-HSA-6811558", "kegg_path:hsa04070", "kegg_path:hsa05010", "kegg_path:hsa05135", "kegg_path:hsa05224", "kegg_path:hsa05168", "R-HSA-389357", "kegg_path:hsa05165", "kegg_path:hsa04910", "kegg_path:hsa05017", "kegg_path:hsa05226", "kegg_path:hsa04613", "kegg_path:hsa01521", "kegg_path:hsa05206", "R-HSA-1266695", "kegg_path:hsa04750", "kegg_path:hsa01524", "kegg_path:hsa04550", "kegg_path:hsa04370", "kegg_path:hsa05214", "kegg_path:hsa04072", "R-HSA-512988", "kegg_path:hsa04066", "kegg_path:hsa04666", "kegg_path:hsa05170", "R-HSA-1430728", "kegg_path:hsa05142", "kegg_path:hsa05020", "R-HSA-9669938", "kegg_path:hsa04151", "kegg_path:hsa04360", "kegg_path:hsa05418", "kegg_path:hsa05212", "kegg_path:hsa04935", "kegg_path:hsa04930", "kegg_path:hsa04024", "R-HSA-9006931", "kegg_path:hsa04662", "kegg_path:hsa04960", "kegg_path:hsa04932", "kegg_path:hsa04914", "R-HSA-451927", "R-HSA-9009391", "kegg_path:hsa04062", "kegg_path:hsa04630", "kegg_path:hsa05160", "kegg_path:hsa04152", "kegg_path:hsa05164", "R-HSA-1280218", "kegg_path:hsa05213", "kegg_path:hsa05223", "R-HSA-1643685", "kegg_path:hsa04660", "kegg_path:hsa04620", "kegg_path:hsa04917", "kegg_path:hsa04625", "kegg_path:hsa04725", "kegg_path:hsa05205", "kegg_path:hsa05230", "kegg_path:hsa05221", "R-HSA-1660499", "kegg_path:hsa04926", "kegg_path:hsa04650", "R-HSA-9670439", "R-HSA-1257604", "kegg_path:hsa04664", "kegg_path:hsa04210", "kegg_path:hsa04213", "R-HSA-556833", "kegg_path:hsa04014", "kegg_path:hsa05218", "kegg_path:hsa05222", "kegg_path:hsa04670", "kegg_path:hsa05210", "kegg_path:hsa04380", "kegg_path:hsa04510", "kegg_path:hsa04810", "R-HSA-2219528", "kegg_path:hsa04068", "kegg_path:hsa05225", "kegg_path:hsa05215", "kegg_path:hsa05146", "kegg_path:hsa04668", "kegg_path:hsa05203", "kegg_path:hsa05162", "kegg_path:hsa04722", "kegg_path:hsa04611" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q92569", "ensembl_id": "ENSG00000117461", "entrez_id": "8503", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.773469" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "744" }, { "type": "SmallVariant", "id": "763" }, { "type": "SmallVariant", "id": "1326" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3R3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIK3R3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "237" }, { "type": "GeneCombination", "id": "240" }, { "type": "GeneCombination", "id": "412" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3R3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PIK3R3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PIK3R3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }