Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/CACNA1H/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "218", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(MYH11, SOD1)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.060472" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI330" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/218/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/218/combinations/?format=api" } }, "genes": { "meta": { "count": 14 }, "data": [ { "type": "Gene", "id": "ADA2" }, { "type": "Gene", "id": "APTX" }, { "type": "Gene", "id": "BICD2" }, { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "CHRNE" }, { "type": "Gene", "id": "LAMB2" }, { "type": "Gene", "id": "MYH11" }, { "type": "Gene", "id": "NME8" }, { "type": "Gene", "id": "PRRT2" }, { "type": "Gene", "id": "QARS1" }, { "type": "Gene", "id": "SLC26A10" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "UNC13A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/218/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/218/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/218/?format=api" } }, { "type": "GeneCombination", "id": "220", "attributes": { "gene_relationship": [ "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:56.327376" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI332" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/220/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/220/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "ADGRB2" }, { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "CHRNB1" }, { "type": "Gene", "id": "GALC" }, { "type": "Gene", "id": "HTT" }, { "type": "Gene", "id": "ITPR1" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "XK" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/220/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/220/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/220/?format=api" } }, { "type": "GeneCombination", "id": "222", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:56.554381" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI334" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/222/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "PGAM4" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SPG11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/222/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/222/?format=api" } }, { "type": "GeneCombination", "id": "373", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:05.085594" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI557" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/373/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/373/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "MAST4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/373/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/373/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/373/?format=api" } }, { "type": "GeneCombination", "id": "711", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:01.172447" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI954" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/711/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/711/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "NEK1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/711/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/711/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/711/?format=api" } }, { "type": "GeneCombination", "id": "715", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:01.272523" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI958" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/715/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/715/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ATXN2" }, { "type": "Gene", "id": "CACNA1H" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/715/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/715/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/715/?format=api" } }, { "type": "GeneCombination", "id": "1036", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.625340" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1468" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1036/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1036/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "CACNA2D4" }, { "type": "Gene", "id": "RELN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1036/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1036/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1036/?format=api" } }, { "type": "GeneCombination", "id": "1028", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Nervous system development", "Developmental Biology", "Axon guidance" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T15:06:24.768598" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1460" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1028/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1028/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CACNA1H" }, { "type": "Gene", "id": "RELN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1028/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1028/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1028/?format=api" } } ] }