Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/715/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ATXN2", "attributes": { "go_molecular_function": [ "RNA binding", "protein C-terminus binding", "protein binding", "epidermal growth factor receptor binding" ], "pathway_id": [ "kegg_path:hsa05014", "kegg_path:hsa05017", "kegg_path:hsa05022" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q99700", "ensembl_id": "ENSG00000204842", "entrez_id": "6311", "chromosome_number": "12", "lastmodified": "2021-10-18T11:00:44.703597" }, "relationships": { "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "CopyNumberVariant", "id": "535" }, { "type": "CopyNumberVariant", "id": "1226" }, { "type": "CopyNumberVariant", "id": "1370" }, { "type": "CopyNumberVariant", "id": "1725" }, { "type": "CopyNumberVariant", "id": "2063" }, { "type": "CopyNumberVariant", "id": "2065" }, { "type": "CopyNumberVariant", "id": "2067" }, { "type": "CopyNumberVariant", "id": "2069" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ATXN2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ATXN2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 11 }, "data": [ { "type": "GeneCombination", "id": "179" }, { "type": "GeneCombination", "id": "182" }, { "type": "GeneCombination", "id": "185" }, { "type": "GeneCombination", "id": "390" }, { "type": "GeneCombination", "id": "428" }, { "type": "GeneCombination", "id": "567" }, { "type": "GeneCombination", "id": "568" }, { "type": "GeneCombination", "id": "712" }, { "type": "GeneCombination", "id": "713" }, { "type": "GeneCombination", "id": "714" }, { "type": "GeneCombination", "id": "715" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ATXN2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ATXN2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ATXN2/?format=api" } }, { "type": "Gene", "id": "CACNA1H", "attributes": { "go_molecular_function": [ "['low voltage-gated calcium channel activity', 'voltage-gated ion channel activity', 'voltage-gated sodium channel activity', 'protein binding', 'metal ion binding', 'scaffold protein binding']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04020", "kegg_path:hsa04713", "kegg_path:hsa04925", "kegg_path:hsa04927", "kegg_path:hsa04929", "kegg_path:hsa04934", "R-HSA-1266738", "R-HSA-375165", "R-HSA-419037", "R-HSA-422475", "R-HSA-9675108" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O95180", "ensembl_id": "None", "entrez_id": "ENSG00000196557", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.379820" }, "relationships": { "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "SmallVariant", "id": "653" }, { "type": "SmallVariant", "id": "674" }, { "type": "SmallVariant", "id": "690" }, { "type": "SmallVariant", "id": "1163" }, { "type": "SmallVariant", "id": "2061" }, { "type": "SmallVariant", "id": "2070" }, { "type": "SmallVariant", "id": "3065" }, { "type": "SmallVariant", "id": "3091" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1H/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1H/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "218" }, { "type": "GeneCombination", "id": "220" }, { "type": "GeneCombination", "id": "222" }, { "type": "GeneCombination", "id": "373" }, { "type": "GeneCombination", "id": "711" }, { "type": "GeneCombination", "id": "715" }, { "type": "GeneCombination", "id": "1036" }, { "type": "GeneCombination", "id": "1028" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1H/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1H/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1H/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }