Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/214/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BBS2", "attributes": { "go_molecular_function": [ "['RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9BXC9", "ensembl_id": "None", "entrez_id": "ENSG00000125124", "chromosome_number": "16", "lastmodified": "2021-10-18T11:00:44.380700" }, "relationships": { "variant_set": { "meta": { "count": 25 }, "data": [ { "type": "SmallVariant", "id": "86" }, { "type": "SmallVariant", "id": "436" }, { "type": "SmallVariant", "id": "85" }, { "type": "SmallVariant", "id": "126" }, { "type": "SmallVariant", "id": "127" }, { "type": "SmallVariant", "id": "128" }, { "type": "SmallVariant", "id": "131" }, { "type": "SmallVariant", "id": "132" }, { "type": "SmallVariant", "id": "165" }, { "type": "SmallVariant", "id": "202" }, { "type": "SmallVariant", "id": "203" }, { "type": "SmallVariant", "id": "255" }, { "type": "SmallVariant", "id": "257" }, { "type": "SmallVariant", "id": "287" }, { "type": "SmallVariant", "id": "341" }, { "type": "SmallVariant", "id": "343" }, { "type": "SmallVariant", "id": "345" }, { "type": "SmallVariant", "id": "350" }, { "type": "SmallVariant", "id": "624" }, { "type": "SmallVariant", "id": "634" }, { "type": "SmallVariant", "id": "894" }, { "type": "SmallVariant", "id": "1349" }, { "type": "SmallVariant", "id": "2417" }, { "type": "SmallVariant", "id": "2602" }, { "type": "SmallVariant", "id": "3036" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 16 }, "data": [ { "type": "GeneCombination", "id": "33" }, { "type": "GeneCombination", "id": "46" }, { "type": "GeneCombination", "id": "47" }, { "type": "GeneCombination", "id": "59" }, { "type": "GeneCombination", "id": "73" }, { "type": "GeneCombination", "id": "94" }, { "type": "GeneCombination", "id": "106" }, { "type": "GeneCombination", "id": "121" }, { "type": "GeneCombination", "id": "212" }, { "type": "GeneCombination", "id": "214" }, { "type": "GeneCombination", "id": "420" }, { "type": "GeneCombination", "id": "422" }, { "type": "GeneCombination", "id": "605" }, { "type": "GeneCombination", "id": "684" }, { "type": "GeneCombination", "id": "1015" }, { "type": "GeneCombination", "id": "1016" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS2/?format=api" } }, { "type": "Gene", "id": "BBS4", "attributes": { "go_molecular_function": [ "alpha-tubulin binding", "dynactin binding", "protein binding", "protein-macromolecule adaptor activity", "beta-tubulin binding", "RNA polymerase II-specific DNA-binding transcription factor binding" ], "pathway_id": [ "R-HSA-5617833", "R-HSA-1852241", "R-HSA-5620922", "R-HSA-5620920" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q96RK4", "ensembl_id": "ENSG00000140463", "entrez_id": "585", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.779872" }, "relationships": { "variant_set": { "meta": { "count": 16 }, "data": [ { "type": "CopyNumberVariant", "id": "1350" }, { "type": "CopyNumberVariant", "id": "1351" }, { "type": "SmallVariant", "id": "2439" }, { "type": "SmallVariant", "id": "123" }, { "type": "SmallVariant", "id": "166" }, { "type": "SmallVariant", "id": "175" }, { "type": "SmallVariant", "id": "200" }, { "type": "SmallVariant", "id": "256" }, { "type": "SmallVariant", "id": "258" }, { "type": "SmallVariant", "id": "632" }, { "type": "SmallVariant", "id": "633" }, { "type": "SmallVariant", "id": "1355" }, { "type": "SmallVariant", "id": "2413" }, { "type": "SmallVariant", "id": "2419" }, { "type": "SmallVariant", "id": "2421" }, { "type": "SmallVariant", "id": "2434" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 13 }, "data": [ { "type": "GeneCombination", "id": "44" }, { "type": "GeneCombination", "id": "59" }, { "type": "GeneCombination", "id": "62" }, { "type": "GeneCombination", "id": "72" }, { "type": "GeneCombination", "id": "94" }, { "type": "GeneCombination", "id": "214" }, { "type": "GeneCombination", "id": "420" }, { "type": "GeneCombination", "id": "421" }, { "type": "GeneCombination", "id": "423" }, { "type": "GeneCombination", "id": "425" }, { "type": "GeneCombination", "id": "605" }, { "type": "GeneCombination", "id": "821" }, { "type": "GeneCombination", "id": "834" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BBS4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BBS4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BBS4/?format=api" } }, { "type": "Gene", "id": "TTC8", "attributes": { "go_molecular_function": [ "['RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q8TAM2", "ensembl_id": "None", "entrez_id": "ENSG00000165533", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.804239" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "117" }, { "type": "SmallVariant", "id": "289" }, { "type": "SmallVariant", "id": "296" }, { "type": "SmallVariant", "id": "297" }, { "type": "SmallVariant", "id": "1368" }, { "type": "SmallVariant", "id": "2468" }, { "type": "SmallVariant", "id": "3491" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TTC8/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TTC8/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "42" }, { "type": "GeneCombination", "id": "104" }, { "type": "GeneCombination", "id": "107" }, { "type": "GeneCombination", "id": "108" }, { "type": "GeneCombination", "id": "214" }, { "type": "GeneCombination", "id": "427" }, { "type": "GeneCombination", "id": "1175" }, { "type": "GeneCombination", "id": "834" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TTC8/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TTC8/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TTC8/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }