Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/214/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "214",
        "attributes": {
            "gene_relationship": [
                "Directly interacting",
                "Same protein complex",
                "Involved in the same disease",
                "Relevant pathways for phenotype",
                "Same pathway"
            ],
            "protein_interactions": [
                "(BBS2, BBS4)",
                "(BBS2, TTC8)",
                "(BBS4, TTC8)"
            ],
            "common_pathways": [
                "Cilium Assembly",
                "Cargo trafficking to the periciliary membrane",
                "Organelle biogenesis and maintenance",
                "BBSome-mediated cargo-targeting to cilium"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:00:55.599924"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI325"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/214/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/214/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 3
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "BBS2"
                    },
                    {
                        "type": "Gene",
                        "id": "BBS4"
                    },
                    {
                        "type": "Gene",
                        "id": "TTC8"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/214/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/214/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/214/?format=api"
        }
    }
}