Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1172/genes/?format=api
{ "data": [ { "type": "Gene", "id": "MKKS", "attributes": { "go_molecular_function": [ "['unfolded protein binding', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'protein binding', 'ATP hydrolysis activity', 'ATP binding']" ], "pathway_id": [ "R-HSA-1852241", "R-HSA-5617833", "R-HSA-5620920", "R-HSA-5620922" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NPJ1", "ensembl_id": "None", "entrez_id": "ENSG00000125863", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.476702" }, "relationships": { "variant_set": { "meta": { "count": 15 }, "data": [ { "type": "SmallVariant", "id": "125" }, { "type": "SmallVariant", "id": "130" }, { "type": "SmallVariant", "id": "133" }, { "type": "SmallVariant", "id": "172" }, { "type": "SmallVariant", "id": "178" }, { "type": "SmallVariant", "id": "293" }, { "type": "SmallVariant", "id": "348" }, { "type": "SmallVariant", "id": "435" }, { "type": "SmallVariant", "id": "437" }, { "type": "SmallVariant", "id": "2437" }, { "type": "SmallVariant", "id": "3039" }, { "type": "SmallVariant", "id": "3040" }, { "type": "SmallVariant", "id": "3042" }, { "type": "SmallVariant", "id": "3484" }, { "type": "SmallVariant", "id": "3493" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MKKS/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MKKS/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "47" }, { "type": "GeneCombination", "id": "61" }, { "type": "GeneCombination", "id": "63" }, { "type": "GeneCombination", "id": "420" }, { "type": "GeneCombination", "id": "45" }, { "type": "GeneCombination", "id": "1018" }, { "type": "GeneCombination", "id": "1019" }, { "type": "GeneCombination", "id": "1017" }, { "type": "GeneCombination", "id": "1172" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MKKS/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MKKS/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MKKS/?format=api" } }, { "type": "Gene", "id": "NPHP4", "attributes": { "go_molecular_function": [ "['structural molecule activity', 'protein binding']" ], "pathway_id": [ "R-HSA-162582", "R-HSA-1852241", "R-HSA-2028269", "R-HSA-5617833", "R-HSA-5620912" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O75161", "ensembl_id": "None", "entrez_id": "ENSG00000131697", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.406649" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "411" }, { "type": "SmallVariant", "id": "412" }, { "type": "SmallVariant", "id": "415" }, { "type": "SmallVariant", "id": "788" }, { "type": "SmallVariant", "id": "3035" }, { "type": "SmallVariant", "id": "3485" }, { "type": "SmallVariant", "id": "3490" }, { "type": "SmallVariant", "id": "3494" }, { "type": "SmallVariant", "id": "3496" }, { "type": "SmallVariant", "id": "3500" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NPHP4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NPHP4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "139" }, { "type": "GeneCombination", "id": "247" }, { "type": "GeneCombination", "id": "1014" }, { "type": "GeneCombination", "id": "1172" }, { "type": "GeneCombination", "id": "1175" }, { "type": "GeneCombination", "id": "1176" }, { "type": "GeneCombination", "id": "1177" }, { "type": "GeneCombination", "id": "1179" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NPHP4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NPHP4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NPHP4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }