Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/NPHP4/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "139", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Monogenic experiments only", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:52.059807" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI212" }, { "type": "Combination", "id": "OLI213" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/139/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/139/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NPHP3" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/139/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/139/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/139/?format=api" } }, { "type": "GeneCombination", "id": "247", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype", "Colocalization", "Same pathway", "Same organelle", "Similar function" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.177595" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI359" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/247/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/247/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CC2D2A" }, { "type": "Gene", "id": "NPHP3" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/247/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/247/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/247/?format=api" } }, { "type": "GeneCombination", "id": "1014", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.521282" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1445" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1014/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1014/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1014/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1014/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1014/?format=api" } }, { "type": "GeneCombination", "id": "1172", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.763057" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1658" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1172/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1172/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MKKS" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1172/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1172/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1172/?format=api" } }, { "type": "GeneCombination", "id": "1175", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.807624" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1661" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1175/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1175/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NPHP4" }, { "type": "Gene", "id": "TTC8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1175/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1175/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1175/?format=api" } }, { "type": "GeneCombination", "id": "1176", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.827150" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1663" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1176/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1176/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NPHP4" }, { "type": "Gene", "id": "USH2A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1176/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1176/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1176/?format=api" } }, { "type": "GeneCombination", "id": "1177", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.842670" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1664" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1177/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1177/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS5" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1177/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1177/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1177/?format=api" } }, { "type": "GeneCombination", "id": "1179", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Anchoring of the basal body to the plasma membrane", "Cilium Assembly", "Signal Transduction" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.872912" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1666" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1179/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1179/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MKS1" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1179/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1179/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1179/?format=api" } } ] }