Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/CHD7/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "39", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 1.318e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 3.113e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0001011, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.788805, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 61769037, "genomic_position_hg38": 60856478, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:40.751045", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.7198C>T", "protein_change": "p.Arg2400Trp", "transcript_id": "NM_017780.3", "dbsnp_id": "rs770959300", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI020" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/39/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/39/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/39/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/39/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/39/?format=api" } }, { "type": "SmallVariant", "id": "275", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 0.0001126, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 2.897e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.001335, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 2.658e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001221 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.97724, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 61765391, "genomic_position_hg38": 60852832, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.141252", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.6107C>T", "protein_change": "p.Pro2036Leu", "transcript_id": "NM_017780.3", "dbsnp_id": "rs369543203", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI132" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/275/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/275/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/275/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/275/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/275/?format=api" } }, { "type": "SmallVariant", "id": "708", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0002, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 5.218e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001151, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": 0.0, "ESP_EA_maf": 0.0001204 }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 0.075881, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 61749394, "genomic_position_hg38": 60836835, "chromosome": "8", "annotation_flag": "automatically_attributed_and_verified", "lastmodified": "2023-06-06T16:57:44.712549", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.4008C>T", "protein_change": "p.Ile1336Ile", "transcript_id": "NM_017780.3", "dbsnp_id": "rs370471177", "variant_effect": "silent" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI339" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/708/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/708/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/708/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/708/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/708/?format=api" } }, { "type": "SmallVariant", "id": "771", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Possibly Damaging", "cadd_prediction": 3.454862, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 61654013, "genomic_position_hg38": 60741454, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.117130", "ref_allele": "A", "alt_allele": "C", "cdna_change": null, "protein_change": "p.Ser8Arg", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI354" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/771/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/771/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/771/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/771/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/771/?format=api" } }, { "type": "SmallVariant", "id": "772", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 2.589489, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 61765669, "genomic_position_hg38": 60853110, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.123509", "ref_allele": "A", "alt_allele": "G", "cdna_change": null, "protein_change": "p.Lys2129Glu", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI354" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/772/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/772/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/772/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/772/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/772/?format=api" } }, { "type": "SmallVariant", "id": "974", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 9.395442, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 61714150, "genomic_position_hg38": 60801591, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:46.358534", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.2440C>T", "protein_change": "p.Gln814Ter", "transcript_id": "NM_017780.3", "dbsnp_id": "rs1554593049", "variant_effect": "nonsense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI457" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/974/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/974/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/974/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/974/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/974/?format=api" } }, { "type": "SmallVariant", "id": "1158", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0062, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0298, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.001, "gnomad_maf": 0.002666, "gnomad_AFR_maf": 6.483e-05, "gnomad_AMR_maf": 0.0001451, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.03468, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 8.878e-06, "gnomad_OTH_maf": 0.00248, "gnomad_SAS_maf": 0.0005895, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 2.323883, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 61655556, "genomic_position_hg38": 60742997, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:47.485493", "ref_allele": "G", "alt_allele": "T", "cdna_change": "c.1565G>T", "protein_change": "p.Gly522Val", "transcript_id": "NM_017780.3", "dbsnp_id": "rs142962579", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI555" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1158/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1158/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1158/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1158/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1158/?format=api" } }, { "type": "SmallVariant", "id": "1215", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0004, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0014, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.001, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.002028, "gnomad_AFR_maf": 0.0007392, "gnomad_AMR_maf": 0.001345, "gnomad_ASJ_maf": 0.0004589, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0002606, "gnomad_NFE_maf": 0.003629, "gnomad_OTH_maf": 0.001645, "gnomad_SAS_maf": 4.649e-05, "ESP_AA_maf": 0.001193, "ESP_EA_maf": 0.005084 }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.331159, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 61769418, "genomic_position_hg38": 60856859, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:47.825128", "ref_allele": "A", "alt_allele": "C", "cdna_change": "c.7579A>C", "protein_change": "p.Met2527Leu", "transcript_id": "NM_017780.3", "dbsnp_id": "rs192129249", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI575" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1215/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1215/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1215/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1215/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1215/?format=api" } }, { "type": "SmallVariant", "id": "1495", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.065566, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 61736442, "genomic_position_hg38": 60823883, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:49.508425", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.3245C>T", "protein_change": "p.Thr1082Ile", "transcript_id": "NM_017780.3", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI689" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1495/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1495/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1495/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1495/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1495/?format=api" } }, { "type": "SmallVariant", "id": "1830", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.557826, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 61768552, "genomic_position_hg38": 60855993, "chromosome": "8", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.560556", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.6955C>T", "protein_change": "p.Arg2319Cys", "transcript_id": "NM_017780.3", "dbsnp_id": "rs121434341", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI836" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1830/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1830/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1830/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1830/gene/?format=api" }, "data": { "type": "Gene", "id": "CHD7" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1830/?format=api" } }, { "type": "SmallVariant", "id": "1853", "attributes": { "frequencies": { "KGP_genomes_maf": null, 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