Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/VAPB/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "178", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:54.013690" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI274" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/178/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/178/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ANG" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/178/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/178/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/178/?format=api" } }, { "type": "GeneCombination", "id": "183", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.156353" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI279" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/183/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/183/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "TARDBP" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/183/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/183/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/183/?format=api" } }, { "type": "GeneCombination", "id": "603", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:18.285927" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI830" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/603/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/603/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "C9orf72" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/603/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/603/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/603/?format=api" } }, { "type": "GeneCombination", "id": "724", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:58:47.465718" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI967" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/724/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/724/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "GRN" }, { "type": "Gene", "id": "PON1" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SPG11" }, { "type": "Gene", "id": "TUBA4A" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/724/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/724/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/724/?format=api" } }, { "type": "GeneCombination", "id": "725", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Directly interacting", "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [ "(SOD1, PFN1)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:58:30.813168" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI968" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/725/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/725/combinations/?format=api" } }, "genes": { "meta": { "count": 7 }, "data": [ { "type": "Gene", "id": "APEX1" }, { "type": "Gene", "id": "GRN" }, { "type": "Gene", "id": "NEK1" }, { "type": "Gene", "id": "PFN1" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "TUBA4A" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/725/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/725/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/725/?format=api" } }, { "type": "GeneCombination", "id": "727", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:56:56.455724" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI970" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/727/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/727/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "FUS" }, { "type": "Gene", "id": "NEK1" }, { "type": "Gene", "id": "PON1" }, { "type": "Gene", "id": "SETX" }, { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "VAPB" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/727/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/727/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/727/?format=api" } } ] }