Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/178/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ANG", "attributes": { "go_molecular_function": [ "protein binding", "endoribonuclease activity" ], "pathway_id": [ "R-HSA-446728", "R-HSA-418990", "kegg_path:hsa05014", "R-HSA-421270", "R-HSA-1500931" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P03950", "ensembl_id": "ENSG00000214274", "entrez_id": "283", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.872102" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "532" }, { "type": "SmallVariant", "id": "542" }, { "type": "SmallVariant", "id": "681" }, { "type": "SmallVariant", "id": "1382" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ANG/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ANG/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 5 }, "data": [ { "type": "GeneCombination", "id": "178" }, { "type": "GeneCombination", "id": "184" }, { "type": "GeneCombination", "id": "221" }, { "type": "GeneCombination", "id": "435" }, { "type": "GeneCombination", "id": "458" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ANG/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ANG/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ANG/?format=api" } }, { "type": "Gene", "id": "VAPB", "attributes": { "go_molecular_function": [ "protein homodimerization activity", "protein binding", "enzyme binding", "beta-tubulin binding", "protein heterodimerization activity", "microtubule binding", "cadherin binding", "FFAT motif binding" ], "pathway_id": [ "R-HSA-1430728", "kegg_path:hsa04979", "R-HSA-428157", "kegg_path:hsa04979", "R-HSA-556833", "kegg_path:hsa05022", "kegg_path:hsa05014", "kegg_path:hsa05014", "kegg_path:hsa05022", "R-HSA-1660661" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O95292", "ensembl_id": "ENSG00000124164", "entrez_id": "9217", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.638178" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "533" }, { "type": "SmallVariant", "id": "1819" }, { "type": "SmallVariant", "id": "2092" }, { "type": "SmallVariant", "id": "2094" }, { "type": "SmallVariant", "id": "2102" }, { "type": "SmallVariant", "id": "2103" }, { "type": "SmallVariant", "id": "2104" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/VAPB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/VAPB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "178" }, { "type": "GeneCombination", "id": "183" }, { "type": "GeneCombination", "id": "603" }, { "type": "GeneCombination", "id": "724" }, { "type": "GeneCombination", "id": "725" }, { "type": "GeneCombination", "id": "727" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/VAPB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/VAPB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/VAPB/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }