Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/RAD52/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "761",
            "attributes": {
                "gene_relationship": [
                    "Same pathway",
                    "Monogenic experiments only",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-03-01T14:36:34.140555"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1041"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/761/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/761/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 5
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "MCM9"
                        },
                        {
                            "type": "Gene",
                            "id": "NCOR2"
                        },
                        {
                            "type": "Gene",
                            "id": "RAD52"
                        },
                        {
                            "type": "Gene",
                            "id": "RAD54L"
                        },
                        {
                            "type": "Gene",
                            "id": "RYR3"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/761/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/761/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/761/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "767",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2022-08-04T14:15:03.527258"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1047"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/767/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/767/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 4
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ADAMTS4"
                        },
                        {
                            "type": "Gene",
                            "id": "DHCR24"
                        },
                        {
                            "type": "Gene",
                            "id": "FSHR"
                        },
                        {
                            "type": "Gene",
                            "id": "RAD52"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/767/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/767/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/767/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "776",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 2,
                "lastmodified": "2022-08-04T14:15:03.908091"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1056"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/776/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/776/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PLEC"
                        },
                        {
                            "type": "Gene",
                            "id": "RAD52"
                        },
                        {
                            "type": "Gene",
                            "id": "RBBP8"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/776/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/776/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/776/?format=api"
            }
        }
    ]
}