Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/LRP1B/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "932",
            "attributes": {
                "gene_relationship": [
                    "Same pathway",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2023-05-16T12:03:26.985458"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1328"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/932/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/932/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "H2BW2"
                        },
                        {
                            "type": "Gene",
                            "id": "KDM6A"
                        },
                        {
                            "type": "Gene",
                            "id": "LRP1B"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/932/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/932/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/932/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1203",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.412570"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1690"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1203/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1203/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 5
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "COL6A6"
                        },
                        {
                            "type": "Gene",
                            "id": "LOXHD1"
                        },
                        {
                            "type": "Gene",
                            "id": "LRP1B"
                        },
                        {
                            "type": "Gene",
                            "id": "PIK3CG"
                        },
                        {
                            "type": "Gene",
                            "id": "SLC4A11"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1203/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1203/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1203/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1204",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.444097"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1691"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1204/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1204/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ALDH1A2"
                        },
                        {
                            "type": "Gene",
                            "id": "CDHR1"
                        },
                        {
                            "type": "Gene",
                            "id": "LRP1B"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1204/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1204/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1204/?format=api"
            }
        }
    ]
}