Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/GNRH1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "242", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:57.954657" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI354" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/242/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/242/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "GNRH1" }, { "type": "Gene", "id": "IL17RD" }, { "type": "Gene", "id": "RNF216" }, { "type": "Gene", "id": "SEMA7A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/242/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/242/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/242/?format=api" } }, { "type": "GeneCombination", "id": "257", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.665277" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI373" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/257/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/257/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "GNRH1" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/257/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/257/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/257/?format=api" } }, { "type": "GeneCombination", "id": "289", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:00.753544" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI430" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/289/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/289/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GADL1" }, { "type": "Gene", "id": "GNRH1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/289/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/289/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/289/?format=api" } }, { "type": "GeneCombination", "id": "851", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2022-08-04T14:15:06.373659" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1168" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/851/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/851/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRH1" }, { "type": "Gene", "id": "WDR11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/851/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/851/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/851/?format=api" } }, { "type": "GeneCombination", "id": "928", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Monogenic experiments only", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.962585" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1324" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/928/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/928/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BMP4" }, { "type": "Gene", "id": "GNRH1" }, { "type": "Gene", "id": "SRA1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/928/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/928/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/928/?format=api" } }, { "type": "GeneCombination", "id": "981", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.338866" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1404" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/981/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/981/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "CCDC141" }, { "type": "Gene", "id": "DCC" }, { "type": "Gene", "id": "GNRH1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/981/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/981/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/981/?format=api" } }, { "type": "GeneCombination", "id": "678", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:28.477963" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI915" }, { "type": "Combination", "id": "OLI1601" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/678/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/678/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "GNRH1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/678/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/678/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/678/?format=api" } }, { "type": "GeneCombination", "id": "1276", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Affecting the same tissue", "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:25:32.403084" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1801" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1276/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1276/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AMHR2" }, { "type": "Gene", "id": "GNRH1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1276/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1276/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1276/?format=api" } } ] }