Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/289/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GADL1", "attributes": { "go_molecular_function": [ "pyridoxal phosphate binding", "aspartate 1-decarboxylase activity", "carbon-carbon lyase activity", "sulfinoalanine decarboxylase activity", "catalytic activity", "carboxy-lyase activity", "lyase activity" ], "pathway_id": [ "kegg_path:hsa00410", "kegg_path:hsa00430", "R-HSA-1430728", "R-HSA-1614635", "kegg_path:hsa00770", "R-HSA-8963693", "R-HSA-71291", "kegg_path:hsa01100", "R-HSA-1614558" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q6ZQY3", "ensembl_id": "ENSG00000144644", "entrez_id": "339896", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.567795" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "920" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GADL1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GADL1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "289" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GADL1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GADL1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GADL1/?format=api" } }, { "type": "Gene", "id": "GNRH1", "attributes": { "go_molecular_function": [ "['hormone activity', 'gonadotropin-releasing hormone receptor binding', 'gonadotropin hormone-releasing hormone activity']" ], "pathway_id": [ "kegg_path:hsa04080", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-162582", "R-HSA-372790", "R-HSA-373076", "R-HSA-375281", "R-HSA-388396", "R-HSA-416476", "R-HSA-500792" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P01148", "ensembl_id": "None", "entrez_id": "ENSG00000147437", "chromosome_number": "8", "lastmodified": "2021-10-18T11:00:44.344397" }, "relationships": { "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "SmallVariant", "id": "774" }, { "type": "SmallVariant", "id": "816" }, { "type": "SmallVariant", "id": "1974" }, { "type": "SmallVariant", "id": "2510" }, { "type": "SmallVariant", "id": "2776" }, { "type": "SmallVariant", "id": "2948" }, { "type": "SmallVariant", "id": "3377" }, { "type": "SmallVariant", "id": "3767" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GNRH1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GNRH1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "242" }, { "type": "GeneCombination", "id": "257" }, { "type": "GeneCombination", "id": "289" }, { "type": "GeneCombination", "id": "851" }, { "type": "GeneCombination", "id": "928" }, { "type": "GeneCombination", "id": "981" }, { "type": "GeneCombination", "id": "678" }, { "type": "GeneCombination", "id": "1276" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GNRH1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GNRH1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GNRH1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }