Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/GJB2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "9", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:45.632482" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI013" }, { "type": "Combination", "id": "OLI060" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/9/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/9/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "TMPRSS3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/9/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/9/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/9/?format=api" } }, { "type": "GeneCombination", "id": "101", "attributes": { "gene_relationship": [ "Indirectly interacting", "Directly interacting", "Same protein complex", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Colocalization", "Same pathway", "Co-expression" ], "protein_interactions": [], "common_pathways": [ "Membrane Trafficking", "Gap junction assembly", "Gap junction trafficking and regulation", "Vesicle-mediated transport" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:49.801339" }, "relationships": { "combination_set": { "meta": { "count": 7 }, "data": [ { "type": "Combination", "id": "OLI135" }, { "type": "Combination", "id": "OLI136" }, { "type": "Combination", "id": "OLI192" }, { "type": "Combination", "id": "OLI193" }, { "type": "Combination", "id": "OLI194" }, { "type": "Combination", "id": "OLI252" }, { "type": "Combination", "id": "OLI406" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/101/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/101/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "GJB3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/101/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/101/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/101/?format=api" } }, { "type": "GeneCombination", "id": "102", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:49.857039" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI137" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/102/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/102/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "PAX3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/102/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/102/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/102/?format=api" } }, { "type": "GeneCombination", "id": "164", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:53.317241" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI251" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/164/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/164/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "MITF" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/164/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/164/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/164/?format=api" } }, { "type": "GeneCombination", "id": "814", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:46:54.987131" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1104" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/814/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/814/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "MPDZ" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/814/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/814/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/814/?format=api" } }, { "type": "GeneCombination", "id": "813", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:47:29.863689" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1103" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/813/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/813/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "MPDZ" }, { "type": "Gene", "id": "SLC26A4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/813/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/813/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/813/?format=api" } }, { "type": "GeneCombination", "id": "811", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:47:53.106651" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1101" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/811/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/811/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "KCNQ4" }, { "type": "Gene", "id": "MPDZ" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/811/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/811/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/811/?format=api" } }, { "type": "GeneCombination", "id": "810", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:48:13.154838" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1100" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/810/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/810/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "CDH23" }, { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "KCNQ4" }, { "type": "Gene", "id": "MPDZ" }, { "type": "Gene", "id": "SLC26A4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/810/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/810/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/810/?format=api" } }, { "type": "GeneCombination", "id": "920", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.911678" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1313" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/920/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/920/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "SLC4A11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/920/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/920/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/920/?format=api" } }, { "type": "GeneCombination", "id": "921", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.915957" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1314" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/921/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/921/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "EYA1" }, { "type": "Gene", "id": "GJB2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/921/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/921/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/921/?format=api" } }, { "type": "GeneCombination", "id": "922", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.920207" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1315" }, { "type": "Combination", "id": "OLI1316" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/922/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/922/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "OTOA" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/922/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/922/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/922/?format=api" } }, { "type": "GeneCombination", "id": "923", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.924426" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1317" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/923/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/923/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "GSDME" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/923/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/923/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/923/?format=api" } }, { "type": "GeneCombination", "id": "924", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:26.934293" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1318" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/924/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/924/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "GJB2" }, { "type": "Gene", "id": "OTOA" }, { "type": "Gene", "id": "OTOF" }, { "type": "Gene", "id": "PJVK" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/924/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/924/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/924/?format=api" } } ] }