Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/102/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GJB2", "attributes": { "go_molecular_function": [ "['gap junction channel activity involved in cell communication by electrical coupling', 'calcium ion binding', 'gap junction channel activity', 'protein binding', 'identical protein binding']" ], "pathway_id": [ "R-HSA-157858", "R-HSA-190704", "R-HSA-190827", "R-HSA-190828", "R-HSA-190861", "R-HSA-190872", "R-HSA-199991", "R-HSA-5653656" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P29033", "ensembl_id": "None", "entrez_id": "ENSG00000165474", "chromosome_number": "13", "lastmodified": "2021-10-18T11:00:44.377664" }, "relationships": { "variant_set": { "meta": { "count": 12 }, "data": [ { "type": "SmallVariant", "id": "24" }, { "type": "SmallVariant", "id": "120" }, { "type": "SmallVariant", "id": "282" }, { "type": "SmallVariant", "id": "283" }, { "type": "SmallVariant", "id": "376" }, { "type": "SmallVariant", "id": "378" }, { "type": "SmallVariant", "id": "490" }, { "type": "SmallVariant", "id": "874" }, { "type": "SmallVariant", "id": "2388" }, { "type": "SmallVariant", "id": "2754" }, { "type": "SmallVariant", "id": "2755" }, { "type": "SmallVariant", "id": "2759" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GJB2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GJB2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 13 }, "data": [ { "type": "GeneCombination", "id": "9" }, { "type": "GeneCombination", "id": "101" }, { "type": "GeneCombination", "id": "102" }, { "type": "GeneCombination", "id": "164" }, { "type": "GeneCombination", "id": "814" }, { "type": "GeneCombination", "id": "813" }, { "type": "GeneCombination", "id": "811" }, { "type": "GeneCombination", "id": "810" }, { "type": "GeneCombination", "id": "920" }, { "type": "GeneCombination", "id": "921" }, { "type": "GeneCombination", "id": "922" }, { "type": "GeneCombination", "id": "923" }, { "type": "GeneCombination", "id": "924" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GJB2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GJB2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GJB2/?format=api" } }, { "type": "Gene", "id": "PAX3", "attributes": { "go_molecular_function": [ "protein binding", "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "sequence-specific double-stranded DNA binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "sequence-specific DNA binding", "DNA-binding transcription factor activity", "DNA binding" ], "pathway_id": [ "R-HSA-4839726", "kegg_path:hsa05202", "R-HSA-3214847", "R-HSA-3247509" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P23760", "ensembl_id": "ENSG00000135903", "entrez_id": "5077", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.713807" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "284" }, { "type": "SmallVariant", "id": "1061" }, { "type": "SmallVariant", "id": "1580" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PAX3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PAX3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "102" }, { "type": "GeneCombination", "id": "346" }, { "type": "GeneCombination", "id": "508" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PAX3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PAX3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PAX3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }