Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/FSHR/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "385", "attributes": { "gene_relationship": [ "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signaling by Nuclear Receptors", "Ovarian steroidogenesis", "Nuclear Receptor transcription pathway", "Generic Transcription Pathway", "Disease", "Metabolism of lipids", "Gene expression (Transcription)", "GPCR downstream signalling", "RNA Polymerase II Transcription", "Metabolism", "Developmental Biology", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:05.648764" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI573" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/385/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "DOCK8" }, { "type": "Gene", "id": "FSHR" }, { "type": "Gene", "id": "NCOR1" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "POR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/385/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/?format=api" } }, { "type": "GeneCombination", "id": "760", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Monogenic experiments only", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BLM, ATM)" ], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:54:01.639477" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1040" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/760/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/760/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "ADAMTS16" }, { "type": "Gene", "id": "ATM" }, { "type": "Gene", "id": "BLM" }, { "type": "Gene", "id": "CYP21A2" }, { "type": "Gene", "id": "FSHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/760/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/760/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/760/?format=api" } }, { "type": "GeneCombination", "id": "767", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2022-08-04T14:15:03.527258" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1047" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/767/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/767/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ADAMTS4" }, { "type": "Gene", "id": "DHCR24" }, { "type": "Gene", "id": "FSHR" }, { "type": "Gene", "id": "RAD52" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/767/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/767/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/767/?format=api" } }, { "type": "GeneCombination", "id": "1230", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:23.020315" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1722" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1230/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1230/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FSHR" }, { "type": "Gene", "id": "SMC1B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1230/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1230/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1230/?format=api" } } ] }