Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/ERBB4/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "634", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:20.029925" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI867" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/634/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/634/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "ERBB4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/634/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/634/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/634/?format=api" } }, { "type": "GeneCombination", "id": "648", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [ "(EGFR, ERBB4)" ], "common_pathways": [ "Nervous system development", "Calcium signaling pathway", "MAPK signaling pathway", "Axon guidance", "ErbB signaling pathway", "Developmental Biology", "PI3K-Akt signaling pathway" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:20.989065" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI882" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/648/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/648/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "EGFR" }, { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "SEMA4D" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/648/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/648/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/648/?format=api" } }, { "type": "GeneCombination", "id": "668", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "PI3K-Akt signaling pathway" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:21.936305" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI905" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/668/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/668/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "RELN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/668/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/668/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/668/?format=api" } }, { "type": "GeneCombination", "id": "670", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Axon guidance", "PI3K-Akt signaling pathway", "Nervous system development", "Developmental Biology" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:22.077290" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI907" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/670/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/670/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "EPHA5" }, { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "RELN" }, { "type": "Gene", "id": "STS" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/670/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/670/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/670/?format=api" } }, { "type": "GeneCombination", "id": "716", "attributes": { "gene_relationship": [ "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:01.297402" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI959" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/716/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/716/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ANXA11" }, { "type": "Gene", "id": "ERBB4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/716/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/716/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/716/?format=api" } }, { "type": "GeneCombination", "id": "762", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2022-08-04T14:15:03.285353" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1042" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/762/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/762/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "PKP1" }, { "type": "Gene", "id": "RYR3" }, { "type": "Gene", "id": "SAMD11" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/762/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/762/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/762/?format=api" } }, { "type": "GeneCombination", "id": "1128", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:28.440950" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1588" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1128/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1128/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "NEK1" }, { "type": "Gene", "id": "TARDBP" }, { "type": "Gene", "id": "VEGFA" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1128/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1128/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1128/?format=api" } }, { "type": "GeneCombination", "id": "1158", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.517913" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1639" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1158/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1158/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ERBB4" }, { "type": "Gene", "id": "SOD1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1158/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1158/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1158/?format=api" } } ] }