Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/716/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ANXA11", "attributes": { "go_molecular_function": [ "calcium ion binding", "protein binding", "calcium-dependent protein binding", "MHC class II protein complex binding", "S100 protein binding", "RNA binding", "phosphatidylethanolamine binding", "calcium-dependent phospholipid binding" ], "pathway_id": [ "kegg_path:hsa05014", "kegg_path:hsa05014" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P50995", "ensembl_id": "ENSG00000122359", "entrez_id": "311", "chromosome_number": "10", "lastmodified": "2022-08-04T14:14:58.961248" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2071" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ANXA11/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ANXA11/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "716" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ANXA11/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ANXA11/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ANXA11/?format=api" } }, { "type": "Gene", "id": "ERBB4", "attributes": { "go_molecular_function": [ "['epidermal growth factor receptor binding', 'protein tyrosine kinase activity', 'protein homodimerization activity', 'transmembrane receptor protein tyrosine kinase activity', 'protein serine/threonine/tyrosine kinase activity', 'transcription cis-regulatory region binding', 'protein binding', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa04010", "kegg_path:hsa04012", "kegg_path:hsa04020", "kegg_path:hsa04151", "kegg_path:hsa05014", "kegg_path:hsa05205" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q15303", "ensembl_id": "None", "entrez_id": "ENSG00000178568", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.341456" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "1896" }, { "type": "SmallVariant", "id": "2072" }, { "type": "SmallVariant", "id": "2262" }, { "type": "SmallVariant", "id": "2263" }, { "type": "SmallVariant", "id": "3353" }, { "type": "SmallVariant", "id": "3447" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ERBB4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ERBB4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "634" }, { "type": "GeneCombination", "id": "648" }, { "type": "GeneCombination", "id": "668" }, { "type": "GeneCombination", "id": "670" }, { "type": "GeneCombination", "id": "716" }, { "type": "GeneCombination", "id": "762" }, { "type": "GeneCombination", "id": "1128" }, { "type": "GeneCombination", "id": "1158" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ERBB4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ERBB4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ERBB4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }