Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/COL6A3/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "100", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Integrin cell surface interactions", "Axon guidance", "Assembly of collagen fibrils and other multimeric structures", "Focal adhesion", "Signaling by Receptor Tyrosine Kinases", "Signaling by PDGF", "ECM-receptor interaction", "Protein digestion and absorption", "ECM proteoglycans", "Developmental Biology", "NCAM signaling for neurite out-growth", "Nervous system development", "Collagen degradation", "Collagen chain trimerization", "Degradation of the extracellular matrix", "NCAM1 interactions", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Human papillomavirus infection", "PI3K-Akt signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:49.766050" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI134" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/100/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/100/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL6A1" }, { "type": "Gene", "id": "COL6A3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/100/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/100/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/100/?format=api" } }, { "type": "GeneCombination", "id": "382", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NCAM1 interactions", "Nervous system development", "Axon guidance", "Developmental Biology", "NCAM signaling for neurite out-growth" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:05.503565" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI570" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/382/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/382/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CACNA1S" }, { "type": "Gene", "id": "COL6A3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/382/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/382/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/382/?format=api" } }, { "type": "GeneCombination", "id": "569", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:16.687445" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI787" }, { "type": "Combination", "id": "OLI788" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/569/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/569/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ABCA7" }, { "type": "Gene", "id": "ADNP" }, { "type": "Gene", "id": "COL6A3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/569/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/569/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/569/?format=api" } }, { "type": "GeneCombination", "id": "575", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Degradation of the extracellular matrix" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:16.976833" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI794" }, { "type": "Combination", "id": "OLI795" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/575/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/575/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL6A3" }, { "type": "Gene", "id": "FBN2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/575/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/575/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/575/?format=api" } }, { "type": "GeneCombination", "id": "1191", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:22.105791" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1678" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1191/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1191/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "COL2A1" }, { "type": "Gene", "id": "COL4A4" }, { "type": "Gene", "id": "COL6A3" }, { "type": "Gene", "id": "TTN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1191/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1191/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1191/?format=api" } }, { "type": "GeneCombination", "id": "1247", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "ECM proteoglycans", "ECM-receptor interaction", "Extracellular matrix organization" ], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:23.319288" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1740" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1247/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1247/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL6A3" }, { "type": "Gene", "id": "DMP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1247/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1247/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1247/?format=api" } } ] }