Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/100/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "100",
        "attributes": {
            "gene_relationship": [
                "Involved in the same disease",
                "Same pathway",
                "Relevant pathways for phenotype"
            ],
            "protein_interactions": [],
            "common_pathways": [
                "Integrin cell surface interactions",
                "Axon guidance",
                "Assembly of collagen fibrils and other multimeric structures",
                "Focal adhesion",
                "Signaling by Receptor Tyrosine Kinases",
                "Signaling by PDGF",
                "ECM-receptor interaction",
                "Protein digestion and absorption",
                "ECM proteoglycans",
                "Developmental Biology",
                "NCAM signaling for neurite out-growth",
                "Nervous system development",
                "Collagen degradation",
                "Collagen chain trimerization",
                "Degradation of the extracellular matrix",
                "NCAM1 interactions",
                "Collagen biosynthesis and modifying enzymes",
                "Collagen formation",
                "Human papillomavirus infection",
                "PI3K-Akt signaling pathway"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2021-10-18T11:00:49.766050"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI134"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/100/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/100/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "COL6A1"
                    },
                    {
                        "type": "Gene",
                        "id": "COL6A3"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/100/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/100/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/100/?format=api"
        }
    }
}