Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/382/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CACNA1S", "attributes": { "go_molecular_function": [ "metal ion binding", "protein binding", "voltage-gated ion channel activity", "voltage-gated calcium channel activity", "high voltage-gated calcium channel activity", "ion channel activity", "calcium channel activity", "calmodulin binding" ], "pathway_id": [ "kegg_path:hsa04261", "kegg_path:hsa04911", "kegg_path:hsa04927", "kegg_path:hsa04935", "kegg_path:hsa04270", "kegg_path:hsa04912", "kegg_path:hsa04929", "kegg_path:hsa04260", "kegg_path:hsa05412", "kegg_path:hsa04727", "kegg_path:hsa05410", "kegg_path:hsa05010", "kegg_path:hsa05020", "kegg_path:hsa04921", "kegg_path:hsa04726", "kegg_path:hsa05414", "kegg_path:hsa04010", "kegg_path:hsa04020", "R-HSA-419037", "kegg_path:hsa04723", "kegg_path:hsa04024", "kegg_path:hsa04925", "kegg_path:hsa05022", "kegg_path:hsa04924", "kegg_path:hsa04022", "kegg_path:hsa04725", "R-HSA-375165", "R-HSA-9675108", "R-HSA-422475", "kegg_path:hsa04934", "R-HSA-1266738" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q13698", "ensembl_id": "ENSG00000081248", "entrez_id": "779", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.729240" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1193" }, { "type": "SmallVariant", "id": "1782" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1S/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1S/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "382" }, { "type": "GeneCombination", "id": "589" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1S/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CACNA1S/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CACNA1S/?format=api" } }, { "type": "Gene", "id": "COL6A3", "attributes": { "go_molecular_function": [ "['extracellular matrix structural constituent conferring tensile strength', 'serine-type endopeptidase inhibitor activity']" ], "pathway_id": [ "kegg_path:hsa04151", "kegg_path:hsa04510", "kegg_path:hsa04512", "kegg_path:hsa04974", "kegg_path:hsa05165", "kegg_path:hsa04151", "kegg_path:hsa04510", "kegg_path:hsa04512", "kegg_path:hsa04974", "kegg_path:hsa05165", "R-HSA-1266738", "R-HSA-1442490", "R-HSA-1474228", "R-HSA-1474244", "R-HSA-1474290", "R-HSA-162582", "R-HSA-1650814", "R-HSA-186797", "R-HSA-2022090", "R-HSA-216083", "R-HSA-3000178", "R-HSA-375165", "R-HSA-419037", "R-HSA-422475", "R-HSA-8948216", "R-HSA-9006934", "R-HSA-9675108" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P12111", "ensembl_id": "None", "entrez_id": "ENSG00000163359", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.996739" }, "relationships": { "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "SmallVariant", "id": "280" }, { "type": "SmallVariant", "id": "1191" }, { "type": "SmallVariant", "id": "1192" }, { "type": "SmallVariant", "id": "1728" }, { "type": "SmallVariant", "id": "1746" }, { "type": "SmallVariant", "id": "3530" }, { "type": "SmallVariant", "id": "3531" }, { "type": "SmallVariant", "id": "3690" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL6A3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL6A3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "100" }, { "type": "GeneCombination", "id": "382" }, { "type": "GeneCombination", "id": "569" }, { "type": "GeneCombination", "id": "575" }, { "type": "GeneCombination", "id": "1191" }, { "type": "GeneCombination", "id": "1247" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/COL6A3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/COL6A3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/COL6A3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }