Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/ATM/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "760",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway",
                    "Monogenic experiments only",
                    "Directly interacting",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [
                    "(BLM, ATM)"
                ],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-03-01T14:54:01.639477"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1040"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/760/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/760/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 5
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ADAMTS16"
                        },
                        {
                            "type": "Gene",
                            "id": "ATM"
                        },
                        {
                            "type": "Gene",
                            "id": "BLM"
                        },
                        {
                            "type": "Gene",
                            "id": "CYP21A2"
                        },
                        {
                            "type": "Gene",
                            "id": "FSHR"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/760/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/760/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/760/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "770",
            "attributes": {
                "gene_relationship": [
                    "Monogenic experiments only",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-03-01T14:53:24.712972"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1050"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/770/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/770/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ATM"
                        },
                        {
                            "type": "Gene",
                            "id": "NCOR2"
                        },
                        {
                            "type": "Gene",
                            "id": "POLG"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/770/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/770/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/770/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "777",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2022-08-04T14:15:03.949587"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1057"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/777/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/777/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ATG4C"
                        },
                        {
                            "type": "Gene",
                            "id": "ATM"
                        },
                        {
                            "type": "Gene",
                            "id": "PRIM1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/777/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/777/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/777/?format=api"
            }
        }
    ]
}