Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/AKR1C3/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "385", "attributes": { "gene_relationship": [ "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signaling by Nuclear Receptors", "Ovarian steroidogenesis", "Nuclear Receptor transcription pathway", "Generic Transcription Pathway", "Disease", "Metabolism of lipids", "Gene expression (Transcription)", "GPCR downstream signalling", "RNA Polymerase II Transcription", "Metabolism", "Developmental Biology", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:05.648764" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI573" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/385/combinations/?format=api" } }, "genes": { "meta": { "count": 6 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "DOCK8" }, { "type": "Gene", "id": "FSHR" }, { "type": "Gene", "id": "NCOR1" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "POR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/385/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/385/?format=api" } }, { "type": "GeneCombination", "id": "1076", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.036679" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1532" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1076/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "GHR" }, { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PLXNA3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1076/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1076/?format=api" } }, { "type": "GeneCombination", "id": "1087", "attributes": { "gene_relationship": [], "protein_interactions": [ "(AKR1C3, AKR1C4)" ], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.117943" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1543" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1087/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1087/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "AKR1C3" }, { "type": "Gene", "id": "AKR1C4" }, { "type": "Gene", "id": "FANCD2" }, { "type": "Gene", "id": "RNF216" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1087/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1087/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1087/?format=api" } } ] }