Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/950/genes/?format=api
{ "data": [ { "type": "Gene", "id": "KISS1R", "attributes": { "go_molecular_function": [ "['G protein-coupled peptide receptor activity', 'neuropeptide receptor activity', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04080", "kegg_path:hsa04929", "R-HSA-162582", "R-HSA-372790", "R-HSA-373076", "R-HSA-375276", "R-HSA-388396", "R-HSA-416476", "R-HSA-500792" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q969F8", "ensembl_id": "None", "entrez_id": "ENSG00000116014", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.814451" }, "relationships": { "variant_set": { "meta": { "count": 14 }, "data": [ { "type": "SmallVariant", "id": "1717" }, { "type": "SmallVariant", "id": "403" }, { "type": "SmallVariant", "id": "803" }, { "type": "SmallVariant", "id": "1884" }, { "type": "SmallVariant", "id": "1944" }, { "type": "SmallVariant", "id": "2666" }, { "type": "SmallVariant", "id": "2669" }, { "type": "SmallVariant", "id": "2700" }, { "type": "SmallVariant", "id": "2705" }, { "type": "SmallVariant", "id": "2715" }, { "type": "SmallVariant", "id": "2835" }, { "type": "SmallVariant", "id": "2851" }, { "type": "SmallVariant", "id": "2937" }, { "type": "SmallVariant", "id": "3367" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KISS1R/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KISS1R/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 10 }, "data": [ { "type": "GeneCombination", "id": "251" }, { "type": "GeneCombination", "id": "259" }, { "type": "GeneCombination", "id": "563" }, { "type": "GeneCombination", "id": "628" }, { "type": "GeneCombination", "id": "887" }, { "type": "GeneCombination", "id": "888" }, { "type": "GeneCombination", "id": "136" }, { "type": "GeneCombination", "id": "943" }, { "type": "GeneCombination", "id": "950" }, { "type": "GeneCombination", "id": "977" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/KISS1R/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/KISS1R/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/KISS1R/?format=api" } }, { "type": "Gene", "id": "NR0B1", "attributes": { "go_molecular_function": [ "['RNA binding', 'transcription factor binding', 'DNA hairpin binding', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'protein domain specific binding', 'nuclear receptor binding', 'protein binding', 'transcription corepressor activity', 'protein homodimerization activity']" ], "pathway_id": [ "kegg_path:hsa04927", "kegg_path:hsa04927" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P51843", "ensembl_id": "None", "entrez_id": "ENSG00000169297", "chromosome_number": "X", "lastmodified": "2022-08-04T14:14:58.385768" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "2397" }, { "type": "SmallVariant", "id": "2516" }, { "type": "SmallVariant", "id": "2852" }, { "type": "SmallVariant", "id": "2981" }, { "type": "SmallVariant", "id": "3263" }, { "type": "SmallVariant", "id": "3304" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NR0B1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NR0B1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "816" }, { "type": "GeneCombination", "id": "854" }, { "type": "GeneCombination", "id": "950" }, { "type": "GeneCombination", "id": "995" }, { "type": "GeneCombination", "id": "1097" }, { "type": "GeneCombination", "id": "1112" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NR0B1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NR0B1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NR0B1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }