Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/KISS1R/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "251", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.425795" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI366" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/251/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/251/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "IL17RD" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/251/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/251/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/251/?format=api" } }, { "type": "GeneCombination", "id": "259", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.827956" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI375" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/259/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/259/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/259/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/259/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/259/?format=api" } }, { "type": "GeneCombination", "id": "563", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "G alpha (q) signalling events", "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:16.478680" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI780" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/563/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/563/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/563/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/563/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/563/?format=api" } }, { "type": "GeneCombination", "id": "628", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "G alpha (q) signalling events", "Signaling by GPCR", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:19.676054" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI861" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/628/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/628/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "B4GAT1" }, { "type": "Gene", "id": "EGFR" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/628/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/628/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/628/?format=api" } }, { "type": "GeneCombination", "id": "887", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.695157" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1264" }, { "type": "Combination", "id": "OLI1596" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/887/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/887/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KISS1R" }, { "type": "Gene", "id": "SOX10" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/887/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/887/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/887/?format=api" } }, { "type": "GeneCombination", "id": "888", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.699508" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1265" }, { "type": "Combination", "id": "OLI1284" }, { "type": "Combination", "id": "OLI1291" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/888/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/888/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/888/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/888/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/888/?format=api" } }, { "type": "GeneCombination", "id": "136", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "GPCR downstream signalling", "Signal Transduction", "Peptide ligand-binding receptors", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.767340" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI208" }, { "type": "Combination", "id": "OLI895" }, { "type": "Combination", "id": "OLI1281" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/136/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/136/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KISS1R" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/136/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/136/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/136/?format=api" } }, { "type": "GeneCombination", "id": "943", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Monogenic experiments only", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "Neuroactive ligand-receptor interaction", "GPCR downstream signalling", "Signal Transduction", "Class A/1 (Rhodopsin-like receptors)", "Peptide ligand-binding receptors", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.092107" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1345" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/943/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/943/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CCKBR" }, { "type": "Gene", "id": "KISS1R" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/943/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/943/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/943/?format=api" } }, { "type": "GeneCombination", "id": "950", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.130714" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1355" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/950/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/950/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KISS1R" }, { "type": "Gene", "id": "NR0B1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/950/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/950/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/950/?format=api" } }, { "type": "GeneCombination", "id": "977", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.311430" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1400" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/977/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/977/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "KISS1R" }, { "type": "Gene", "id": "PNPLA6" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/977/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/977/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/977/?format=api" } } ] }