Variant List
This API endpoint handles listing (/variants) and retrieval (/variants/<ID>/) of genetic variants from the database
GET /api/genes/KISS1R/variants/?format=api
{ "data": [ { "type": "SmallVariant", "id": "1717", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": null, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": null, "genomic_position_hg38": null, "chromosome": "19", "annotation_flag": "not_found_in_databases", "lastmodified": "2021-10-18T11:01:16.471122", "ref_allele": null, "alt_allele": null, "cdna_change": null, "protein_change": "p.Gly56AlafsTer21", "transcript_id": null, "dbsnp_id": "NA", "variant_effect": "frameshift" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI780" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1717/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1717/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1717/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1717/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1717/?format=api" } }, { "type": "SmallVariant", "id": "403", "attributes": { "frequencies": { "KGP_genomes_maf": 0.02, "KGP_genomes_AFR_maf": 0.0726, "KGP_genomes_AMR_maf": 0.0043, "KGP_genomes_EAS_maf": 0.0, "KGP_genomes_EUR_maf": 0.001, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.004558, "gnomad_AFR_maf": 0.06748, "gnomad_AMR_maf": 0.003152, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0003742, "gnomad_NFE_maf": 0.001112, "gnomad_OTH_maf": 0.00199, "gnomad_SAS_maf": 0.0001626, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 0.91874, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 919933, "genomic_position_hg38": 919933, "chromosome": "19", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:42.894356", "ref_allele": "G", "alt_allele": "A", "cdna_change": "c.565G>A", "protein_change": "p.Ala189Thr", "transcript_id": "NM_032551.4", "dbsnp_id": "rs73507527", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI208" }, { "type": "Combination", "id": "OLI375" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/403/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/403/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/403/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/403/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/403/?format=api" } }, { "type": "SmallVariant", "id": "803", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 3.465e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 7.094e-05, "gnomad_OTH_maf": 0.0002155, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.675996, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 919949, "genomic_position_hg38": 919949, "chromosome": "19", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:45.303384", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.581C>A", "protein_change": "p.Ala194Asp", "transcript_id": "NM_032551.4", "dbsnp_id": "rs397514699", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI366" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/803/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/803/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/803/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/803/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/803/?format=api" } }, { "type": "SmallVariant", "id": "1884", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 3.562358, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 919521, "genomic_position_hg38": 919521, "chromosome": "19", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:51.898811", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.401C>T", "protein_change": "p.Thr134Ile", "transcript_id": "NM_032551.4", "dbsnp_id": "NA", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI861" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1884/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1884/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1884/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1884/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1884/?format=api" } }, { "type": "SmallVariant", "id": "1944", "attributes": { "frequencies": { "KGP_genomes_maf": 0.0014, "KGP_genomes_AFR_maf": 0.0, "KGP_genomes_AMR_maf": 0.0, "KGP_genomes_EAS_maf": 0.0069, "KGP_genomes_EUR_maf": 0.0, "KGP_genomes_SAS_maf": 0.0, "gnomad_maf": 0.0003334, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 3.353e-05, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.004172, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.233103, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 919955, "genomic_position_hg38": 919955, "chromosome": "19", "annotation_flag": "automatically_attributed", "lastmodified": "2023-06-06T16:57:52.282855", "ref_allele": "C", "alt_allele": "A", "cdna_change": "c.587C>A", "protein_change": "p.Pro196His", "transcript_id": "NM_032551.4", "dbsnp_id": "rs572007403", "variant_effect": "missense" }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI895" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/1944/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/1944/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/1944/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/1944/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/1944/?format=api" } }, { "type": "SmallVariant", "id": "2666", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 2.700781, "mutationtaster_prediction": null }, "status": "CU", "genomic_position_hg19": 919920, "genomic_position_hg38": 919920, "chromosome": "19", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.505504", "ref_allele": "AC", "alt_allele": "A", "cdna_change": "c.555del", "protein_change": "p.Pro187ArgfsTer132", "transcript_id": "NM_032551.5", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1264" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2666/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2666/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2666/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2666/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2666/?format=api" } }, { "type": "SmallVariant", "id": "2669", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Benign", "cadd_prediction": 1.014545, "mutationtaster_prediction": "Polymorphism" }, "status": "CU", "genomic_position_hg19": 919883, "genomic_position_hg38": 919883, "chromosome": "19", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.524405", "ref_allele": "C", "alt_allele": "T", "cdna_change": "c.515C>T", "protein_change": "p.Ala172Val", "transcript_id": "NM_032551.5", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1265" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2669/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2669/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2669/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2669/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2669/?format=api" } }, { "type": "SmallVariant", "id": "2700", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": null, "gnomad_AFR_maf": null, "gnomad_AMR_maf": null, "gnomad_ASJ_maf": null, "gnomad_EAS_maf": null, "gnomad_FIN_maf": null, "gnomad_NFE_maf": null, "gnomad_OTH_maf": null, "gnomad_SAS_maf": null, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Deleterious", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.113125, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 919544, "genomic_position_hg38": 919544, "chromosome": "19", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.712438", "ref_allele": "T", "alt_allele": "G", "cdna_change": "c.424T>G", "protein_change": "p.Tyr142Asp", "transcript_id": "NM_032551.5", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1281" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2700/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2700/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2700/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2700/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2700/?format=api" } }, { "type": "SmallVariant", "id": "2705", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 6.809e-05, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 0.0001122, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": null, "pp2_hvar_prediction": null, "cadd_prediction": 1.125806, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 920746, "genomic_position_hg38": 920746, "chromosome": "19", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.743993", "ref_allele": "T", "alt_allele": "A", "cdna_change": "c.1195T>A", "protein_change": "p.Ter399Arg", "transcript_id": "NM_032551.5", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1284" }, { "type": "Combination", "id": "OLI1400" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2705/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2705/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2705/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2705/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2705/?format=api" } }, { "type": "SmallVariant", "id": "2715", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, "KGP_genomes_AMR_maf": null, "KGP_genomes_EAS_maf": null, "KGP_genomes_EUR_maf": null, "KGP_genomes_SAS_maf": null, "gnomad_maf": 5.637e-06, "gnomad_AFR_maf": 0.0, "gnomad_AMR_maf": 0.0, "gnomad_ASJ_maf": 0.0, "gnomad_EAS_maf": 0.0, "gnomad_FIN_maf": 0.0, "gnomad_NFE_maf": 1.307e-05, "gnomad_OTH_maf": 0.0, "gnomad_SAS_maf": 0.0, "ESP_AA_maf": null, "ESP_EA_maf": null }, "predictions": { "sift_prediction": "Tolerated", "pp2_hvar_prediction": "Damaging", "cadd_prediction": 4.233035, "mutationtaster_prediction": "Disease causing" }, "status": "CU", "genomic_position_hg19": 919527, "genomic_position_hg38": 919527, "chromosome": "19", "annotation_flag": null, "lastmodified": "2023-06-06T16:57:56.804786", "ref_allele": "T", "alt_allele": "G", "cdna_change": "c.407T>G", "protein_change": "p.Met136Arg", "transcript_id": "NM_032551.5", "dbsnp_id": "NA", "variant_effect": null }, "relationships": { "in_combination": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1291" } ], "links": { "self": "https://olida.ibsquare.be/api/variants/2715/relationships/in_combination?format=api", "related": "https://olida.ibsquare.be/api/variants/2715/combinations/?format=api" } }, "gene_name": { "links": { "self": "https://olida.ibsquare.be/api/variants/2715/relationships/gene_name?format=api", "related": "https://olida.ibsquare.be/api/variants/2715/gene/?format=api" }, "data": { "type": "Gene", "id": "KISS1R" } } }, "links": { "self": "https://olida.ibsquare.be/api/variants/2715/?format=api" } }, { "type": "SmallVariant", "id": "2835", "attributes": { "frequencies": { "KGP_genomes_maf": null, "KGP_genomes_AFR_maf": null, 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